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vorinostat and Leishmaniasis, Visceral

vorinostat has been researched along with Leishmaniasis, Visceral in 1 studies

Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.

Research Excerpts

ExcerptRelevanceReference
"There is currently no satisfactory treatment for visceral leishmaniasis; the disease is thus in desperate need of novel drugs."1.51A nanodelivered Vorinostat derivative is a promising oral compound for the treatment of visceral leishmaniasis. ( Belmonte-Reche, E; Corpas-López, V; de Pedro, N; Díaz-Gavilán, M; Franco-Montalbán, F; Gómez-Vidal, JA; López-Viota, J; López-Viota, M; Martín-Sánchez, J; Merino-Espinosa, G; Morillas-Márquez, F; Pérez-Del Palacio, J, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corpas-López, V1
Díaz-Gavilán, M1
Franco-Montalbán, F1
Merino-Espinosa, G1
López-Viota, M1
López-Viota, J1
Belmonte-Reche, E1
Pérez-Del Palacio, J1
de Pedro, N1
Gómez-Vidal, JA1
Morillas-Márquez, F1
Martín-Sánchez, J1

Other Studies

1 other study available for vorinostat and Leishmaniasis, Visceral

ArticleYear
A nanodelivered Vorinostat derivative is a promising oral compound for the treatment of visceral leishmaniasis.
    Pharmacological research, 2019, Volume: 139

    Topics: Administration, Oral; Anilides; Animals; Antiprotozoal Agents; Drug Delivery Systems; Female; Gold;

2019