vorinostat has been researched along with Koch's Disease in 2 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " tuberculosis H37Rv cultures were exposed to VPA or SAHA over 6 days, in the presence or absence of isoniazid (INH) and rifampicin (RIF)." | 7.88 | Evaluation of the efficacy of valproic acid and suberoylanilide hydroxamic acid (vorinostat) in enhancing the effects of first-line tuberculosis drugs against intracellular Mycobacterium tuberculosis. ( Maeurer, M; Rao, M; Valentini, D; Zumla, A, 2018) |
| " tuberculosis H37Rv cultures were exposed to VPA or SAHA over 6 days, in the presence or absence of isoniazid (INH) and rifampicin (RIF)." | 3.88 | Evaluation of the efficacy of valproic acid and suberoylanilide hydroxamic acid (vorinostat) in enhancing the effects of first-line tuberculosis drugs against intracellular Mycobacterium tuberculosis. ( Maeurer, M; Rao, M; Valentini, D; Zumla, A, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, C | 1 |
| Cai, Y | 1 |
| Zhu, J | 1 |
| Zhang, L | 1 |
| Xing, A | 1 |
| Pan, L | 1 |
| Jia, H | 1 |
| Mo, S | 1 |
| Feng, CG | 1 |
| Shen, H | 1 |
| Chen, X | 1 |
| Zhang, Z | 1 |
| Rao, M | 1 |
| Valentini, D | 1 |
| Zumla, A | 1 |
| Maeurer, M | 1 |
2 other studies available for vorinostat and Koch's Disease
| Article | Year |
|---|---|
Histone deacetylase inhibitors impair the host immune response against Mycobacterium tuberculosis infection.
Topics: Animals; Autophagy; Bacterial Load; Cells, Cultured; Colony Count, Microbial; Disease Susceptibility | 2019 |
Evaluation of the efficacy of valproic acid and suberoylanilide hydroxamic acid (vorinostat) in enhancing the effects of first-line tuberculosis drugs against intracellular Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Isoniazid; Macropha | 2018 |