vorinostat has been researched along with Insulin Resistance in 2 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin resistance has been reported as a strong risk factor for Alzheimer's disease." | 1.43 | Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice. ( Sharma, S; Taliyan, R, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grigolon, G | 1 |
| Araldi, E | 1 |
| Erni, R | 1 |
| Wu, JY | 1 |
| Thomas, C | 1 |
| La Fortezza, M | 1 |
| Laube, B | 1 |
| Pöhlmann, D | 1 |
| Stoffel, M | 1 |
| Zarse, K | 1 |
| Carreira, EM | 1 |
| Ristow, M | 1 |
| Fischer, F | 1 |
| Sharma, S | 1 |
| Taliyan, R | 1 |
2 other studies available for vorinostat and Insulin Resistance
| Article | Year |
|---|---|
Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan.
Topics: Animals; Animals, Genetically Modified; Blood Glucose; Caenorhabditis elegans; Caenorhabditis elegan | 2022 |
Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognition Disorder | 2016 |