vorinostat has been researched along with Glaucoma in 3 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
Excerpt | Relevance | Reference |
---|---|---|
"This study was conducted to evaluate cytotoxicity due to co-treatment with low-dose Mitomycin-C (MMC) and the histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA) for glaucoma filtration surgery." | 3.76 | An experimental study of rabbit conjunctival epithelial toxicity using co-treatment with mitomycin-C and a histone deacetylase inhibitor. ( Ahn, HB; Jeung, WJ; Kim, TH; Oh, HC; Park, WC; Rho, JH; Rho, SH; Yoo, YH, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sharma, A | 1 |
Anumanthan, G | 1 |
Reyes, M | 1 |
Chen, H | 1 |
Brubaker, JW | 1 |
Siddiqui, S | 1 |
Gupta, S | 1 |
Rieger, FG | 1 |
Mohan, RR | 1 |
Kim, TH | 2 |
Oh, HC | 1 |
Yoo, YH | 2 |
Rho, JH | 2 |
Park, WC | 2 |
Ahn, HB | 1 |
Jeung, WJ | 1 |
Rho, SH | 2 |
Kim, SW | 1 |
Woo, JM | 1 |
Lee, DJ | 1 |
Park, JM | 1 |
Jeong, WJ | 1 |
3 other studies available for vorinostat and Glaucoma
Article | Year |
---|---|
Epigenetic Modification Prevents Excessive Wound Healing and Scar Formation After Glaucoma Filtration Surgery.
Topics: Analysis of Variance; Animals; Blotting, Western; Cicatrix; Collagen; Conjunctiva; Cornea; Disease M | 2016 |
An experimental study of rabbit conjunctival epithelial toxicity using co-treatment with mitomycin-C and a histone deacetylase inhibitor.
Topics: Alkylating Agents; Animals; Apoptosis; Cells, Cultured; Conjunctiva; Drug Therapy, Combination; Epit | 2010 |
Co-treatment of suberoylanilide hydroxamic acid and mitomycin-C induces the apoptosis of rabbit tenon's capsule fibroblast and improves the outcome of glaucoma filtration surgery.
Topics: Alkylating Agents; Animals; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Caspase 3; C | 2008 |