vorinostat has been researched along with Genetic Predisposition in 1 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "AKR1C3 protein is elevated within prostate cancer tissue, it contributes to the formation of androgens and downstream stimulation of the androgen receptor (AR)." | 1.43 | Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells. ( Battaglia, S; Bunce, CM; Campbell, MJ; Doig, CL; Khanim, FL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doig, CL | 1 |
| Battaglia, S | 1 |
| Khanim, FL | 1 |
| Bunce, CM | 1 |
| Campbell, MJ | 1 |
1 other study available for vorinostat and Genetic Predisposition
| Article | Year |
|---|---|
Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Cell Line, Tumor; Cell Prol | 2016 |