Page last updated: 2024-11-04

vorinostat and Ependymoma

vorinostat has been researched along with Ependymoma in 2 studies

Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Ependymoma: Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Gorsi, HS1
Toll, SA1
Sood, S1
Miler, S1
Altinok, D1
Kumar-Sinha, C1
Mody, R1
Yankelevich, M1
Milde, T1
Kleber, S1
Korshunov, A1
Witt, H1
Hielscher, T1
Koch, P1
Kopp, HG1
Jugold, M1
Deubzer, HE1
Oehme, I1
Lodrini, M1
Gröne, HJ1
Benner, A1
Brüstle, O1
Gilbertson, RJ1
von Deimling, A1
Kulozik, AE1
Pfister, SM1
Martin-Villalba, A1
Witt, O1

Other Studies

2 other studies available for vorinostat and Ependymoma

ArticleYear
Ongoing Response in a Multiply Relapsed Metastatic Posterior Fossa Ependymoma A After Vorinostat and Concomitant Irradiation.
    Journal of pediatric hematology/oncology, 2022, Mar-01, Volume: 44, Issue:2

    Topics: Child, Preschool; Combined Modality Therapy; Ependymoma; Histone Deacetylase Inhibitors; Humans; Mal

2022
A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
    Acta neuropathologica, 2011, Volume: 122, Issue:5

    Topics: Animals; Cell Differentiation; Cell Line, Tumor; Ependymoma; Gene Expression Profiling; Histone Deac

2011