vorinostat has been researched along with Electrocardiogram QT Prolonged in 2 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vorinostat is a histone deacetylase inhibitor used in the treatment of recurrent or persistent cases of cutaneous T-cell lymphoma (CTCL)." | 4.88 | QT interval prolongation and torsades de pointes in a patient undergoing treatment with vorinostat: a case report and review of the literature. ( Lynch, DR; Newby, LK; Washam, JB, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, Q | 1 |
| Patel, D | 1 |
| Zhang, X | 1 |
| Veenstra, RD | 1 |
| Lynch, DR | 1 |
| Washam, JB | 1 |
| Newby, LK | 1 |
1 review available for vorinostat and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
QT interval prolongation and torsades de pointes in a patient undergoing treatment with vorinostat: a case report and review of the literature.
Topics: Antineoplastic Agents; Doxepin; Electrocardiography; Histone Deacetylase Inhibitors; Humans; Hydroxa | 2012 |
1 other study available for vorinostat and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Changes in cardiac Nav1.5 expression, function, and acetylation by pan-histone deacetylase inhibitors.
Topics: Animals; Animals, Newborn; Arrhythmias, Cardiac; Blotting, Western; Depsipeptides; Gap Junctions; He | 2016 |