vorinostat has been researched along with Deficiency, Mental in 2 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental diseases associated with various gene mutations." | 1.62 | Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model. ( Aljazi, MB; Gao, Y; He, J; Wu, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, Y | 1 |
| Aljazi, MB | 1 |
| Wu, Y | 1 |
| He, J | 1 |
| Kennedy, AJ | 1 |
| Rahn, EJ | 1 |
| Paulukaitis, BS | 1 |
| Savell, KE | 1 |
| Kordasiewicz, HB | 1 |
| Wang, J | 1 |
| Lewis, JW | 1 |
| Posey, J | 1 |
| Strange, SK | 1 |
| Guzman-Karlsson, MC | 1 |
| Phillips, SE | 1 |
| Decker, K | 1 |
| Motley, ST | 1 |
| Swayze, EE | 1 |
| Ecker, DJ | 1 |
| Michael, TP | 1 |
| Day, JJ | 1 |
| Sweatt, JD | 1 |
2 other studies available for vorinostat and Deficiency, Mental
| Article | Year |
|---|---|
Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model.
Topics: Animals; Autism Spectrum Disorder; Cognitive Dysfunction; Disease Models, Animal; DNA-Binding Protei | 2021 |
Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.
Topics: Animals; Autistic Disorder; CpG Islands; Disease Models, Animal; DNA Methylation; Facies; Gene Expre | 2016 |