vorinostat has been researched along with Deaf Mutism in 1 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Heterozygous deletion of this alternative exon of mouse Rest causes hair cell degeneration and deafness, and the HDAC inhibitor SAHA (Vorinostat) rescues the hearing of these mice." | 3.88 | Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness. ( Bánfi, B; Boger, ET; Friedman, TB; Kelley, MW; Kelly, MC; Morell, RJ; Nakano, Y; Rehman, AU, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakano, Y | 1 |
| Kelly, MC | 1 |
| Rehman, AU | 1 |
| Boger, ET | 1 |
| Morell, RJ | 1 |
| Kelley, MW | 1 |
| Friedman, TB | 1 |
| Bánfi, B | 1 |
1 other study available for vorinostat and Deaf Mutism
| Article | Year |
|---|---|
Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness.
Topics: Alternative Splicing; Animals; Cell Line; Deafness; Exons; Gene Expression Regulation; Hair Cells, A | 2018 |