vorinostat has been researched along with Cystic Fibrosis of Pancreas in 5 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (80.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
Authors | Studies |
---|---|
Hutt, DM | 1 |
Herman, D | 1 |
Rodrigues, AP | 1 |
Noel, S | 1 |
Pilewski, JM | 1 |
Matteson, J | 1 |
Hoch, B | 1 |
Kellner, W | 1 |
Kelly, JW | 1 |
Schmidt, A | 1 |
Thomas, PJ | 1 |
Matsumura, Y | 1 |
Skach, WR | 1 |
Gentzsch, M | 1 |
Riordan, JR | 1 |
Sorscher, EJ | 2 |
Okiyoneda, T | 1 |
Yates, JR | 1 |
Lukacs, GL | 1 |
Frizzell, RA | 1 |
Manning, G | 1 |
Gottesfeld, JM | 1 |
Balch, WE | 1 |
Barone, S | 1 |
Cassese, E | 1 |
Alfano, AI | 1 |
Brindisi, M | 1 |
Summa, V | 1 |
Bergougnoux, A | 1 |
Petit, A | 1 |
Knabe, L | 1 |
Bribes, E | 1 |
Chiron, R | 1 |
De Sario, A | 1 |
Claustres, M | 1 |
Molinari, N | 1 |
Vachier, I | 1 |
Taulan-Cadars, M | 1 |
Bourdin, A | 1 |
Chung, WJ | 1 |
Goeckeler-Fried, JL | 1 |
Havasi, V | 1 |
Chiang, A | 1 |
Rowe, SM | 1 |
Plyler, ZE | 1 |
Hong, JS | 1 |
Mazur, M | 1 |
Piazza, GA | 1 |
Keeton, AB | 1 |
White, EL | 1 |
Rasmussen, L | 1 |
Weissman, AM | 1 |
Denny, RA | 1 |
Brodsky, JL | 1 |
Sondo, E | 1 |
Tomati, V | 1 |
Caci, E | 1 |
Esposito, AI | 1 |
Pfeffer, U | 1 |
Pedemonte, N | 1 |
Galietta, LJ | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Defining Epigenetic Regulation of Immunity in Alpha-1 Anti-trypsin Deficiency[NCT02691611] | 39 participants (Actual) | Observational | 2015-12-31 | Active, not recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for vorinostat and Cystic Fibrosis of Pancreas
Article | Year |
---|---|
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histone Deacetylase 6 | 2022 |
4 other studies available for vorinostat and Cystic Fibrosis of Pancreas
Article | Year |
---|---|
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.
Topics: Animals; Bronchi; Cell Membrane; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conducta | 2010 |
The HDAC inhibitor SAHA does not rescue CFTR membrane expression in Cystic Fibrosis.
Topics: Cell Membrane; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Fem | 2017 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu | 2016 |
Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling.
Topics: Aminacrine; Bacterial Proteins; Benzamides; Cell Line; Cell Membrane; Chlorides; Ciclopirox; Cold Te | 2011 |