vorinostat has been researched along with Cryptosporidiosis in 2 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Cryptosporidiosis: Intestinal infection with organisms of the genus CRYPTOSPORIDIUM. It occurs in both animals and humans. Symptoms include severe DIARRHEA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings suggest the potential for repurposing of vorinostat to treat cryptosporidiosis, and imply that the parasite HDAC can be explored for developing more selective anticryptosporidial therapeutics." | 7.88 | The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases. ( Guo, F; McNair, NN; Mead, JR; Zhang, H; Zhu, G, 2018) |
| "These findings suggest the potential for repurposing of vorinostat to treat cryptosporidiosis, and imply that the parasite HDAC can be explored for developing more selective anticryptosporidial therapeutics." | 3.88 | The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases. ( Guo, F; McNair, NN; Mead, JR; Zhang, H; Zhu, G, 2018) |
| "Cryptosporidiosis is a significant diarrheal disease in humans and animals." | 1.91 | Cost-effective In Vivo and In Vitro Mouse Models for Evaluating Anticryptosporidial Drug Efficacy: Assessing Vorinostat, Docetaxel, and Baicalein. ( Liu, M; Wang, D; Wu, X; Yin, J; Zhang, D; Zhang, Y; Zhu, G, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, M | 1 |
| Zhang, D | 1 |
| Wang, D | 1 |
| Wu, X | 1 |
| Zhang, Y | 1 |
| Yin, J | 1 |
| Zhu, G | 2 |
| Guo, F | 1 |
| Zhang, H | 1 |
| McNair, NN | 1 |
| Mead, JR | 1 |
2 other studies available for vorinostat and Cryptosporidiosis
| Article | Year |
|---|---|
Cost-effective In Vivo and In Vitro Mouse Models for Evaluating Anticryptosporidial Drug Efficacy: Assessing Vorinostat, Docetaxel, and Baicalein.
Topics: Animals; Antiprotozoal Agents; Cost-Benefit Analysis; Cryptosporidiosis; Cryptosporidium; Cryptospor | 2023 |
The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases.
Topics: Animals; Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium parvum; Drug Discovery; Histone De | 2018 |