vorinostat has been researched along with Cryptogenic Fibrosing Alveolitis in 4 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Idiopathic pulmonary fibrosis (IPF) is a deadly disease characterized by chronic inflammation and excessive collagen accumulation in the lung." | 1.39 | Histone deacetylase inhibition downregulates collagen 3A1 in fibrotic lung fibroblasts. ( Hock, T; Liu, H; Sanders, YY; Thannickal, VJ; Zhang, X, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, W | 1 |
| Yao, X | 1 |
| Ouyang, P | 1 |
| Dong, N | 1 |
| Wu, D | 1 |
| Jiang, X | 1 |
| Wu, Z | 1 |
| Zhang, C | 1 |
| Xu, Z | 1 |
| Tang, Y | 1 |
| Zou, S | 1 |
| Liu, M | 1 |
| Li, J | 1 |
| Zeng, M | 1 |
| Lin, P | 1 |
| Cheng, F | 1 |
| Huang, J | 1 |
| Kamio, K | 1 |
| Azuma, A | 1 |
| Usuki, J | 1 |
| Matsuda, K | 1 |
| Inomata, M | 1 |
| Nishijima, N | 1 |
| Itakura, S | 1 |
| Hayashi, H | 1 |
| Kashiwada, T | 1 |
| Kokuho, N | 1 |
| Atsumi, K | 1 |
| Yamaguchi, T | 1 |
| Fujita, K | 1 |
| Saito, Y | 1 |
| Abe, S | 1 |
| Kubota, K | 1 |
| Gemma, A | 1 |
| Zhang, X | 1 |
| Liu, H | 2 |
| Hock, T | 1 |
| Thannickal, VJ | 2 |
| Sanders, YY | 2 |
| Hagood, JS | 1 |
| Zhang, W | 1 |
| Ambalavanan, N | 1 |
4 other studies available for vorinostat and Cryptogenic Fibrosing Alveolitis
| Article | Year |
|---|---|
Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis.
Topics: Acute Lung Injury; Animals; Epoxide Hydrolases; Female; Histone Deacetylase Inhibitors; Idiopathic P | 2017 |
XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts.
Topics: Benzamides; Cells, Cultured; Extracellular Matrix; Fibroblasts; Gene Silencing; Histone Deacetylase | 2017 |
Histone deacetylase inhibition downregulates collagen 3A1 in fibrotic lung fibroblasts.
Topics: Animals; Cells, Cultured; Chromatin; Collagen Type III; Down-Regulation; Fibroblasts; Histone Deacet | 2013 |
Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice.
Topics: Animals; Apoptosis; Bleomycin; Cell Proliferation; Cell Survival; DNA Methylation; Fibroblasts; Hist | 2014 |