Page last updated: 2024-11-04

vorinostat and Cognitive Dysfunction

vorinostat has been researched along with Cognitive Dysfunction in 7 studies

Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.

Research Excerpts

ExcerptRelevanceReference
"Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental diseases associated with various gene mutations."1.62Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model. ( Aljazi, MB; Gao, Y; He, J; Wu, Y, 2021)
"Depression is a disabling psychiatric disorder affecting millions of people all around the world."1.62SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class. ( Amini-Khoei, H; Dehpour, AR; Ershadi, ASB; Hosseini, MJ, 2021)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's6 (85.71)2.80

Authors

AuthorsStudies
Kaur, N1
Fang, YC1
Lee, HY1
Singh, A1
Nepali, K1
Lin, MH1
Yeh, TK1
Lai, MJ1
Chan, L1
Tu, YK1
Banerjee, S1
Hu, CJ1
Liou, JP1
Gao, Y1
Aljazi, MB1
Wu, Y1
He, J1
Luo, F1
Min, J1
Wu, J1
Zuo, Z1
Ershadi, ASB1
Amini-Khoei, H1
Hosseini, MJ1
Dehpour, AR1
Fang, P1
Chen, C1
Zheng, F1
Jia, J1
Chen, T1
Zhu, J1
Chang, J1
Zhang, Z1
Takada, N1
Nakamura, Y1
Ikeda, K1
Takaoka, N1
Hisaoka-Nakashima, K1
Sanoh, S1
Kotake, Y1
Nakata, Y1
Morioka, N1
Zhang, D1
Xue, B1
You, J1
Zhang, B1
Chai, G1

Other Studies

7 other studies available for vorinostat and Cognitive Dysfunction

ArticleYear
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment.
    European journal of medicinal chemistry, 2020, Feb-01, Volume: 187

    Topics: Animals; Azepines; Cell Line, Tumor; Clomipramine; Cognitive Dysfunction; Dementia, Vascular; Dose-R

2020
Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model.
    Neuroscience letters, 2021, 11-01, Volume: 764

    Topics: Animals; Autism Spectrum Disorder; Cognitive Dysfunction; Disease Models, Animal; DNA-Binding Protei

2021
Histone Deacetylases May Mediate Surgery-Induced Impairment of Learning, Memory, and Dendritic Development.
    Molecular neurobiology, 2020, Volume: 57, Issue:9

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Dendrites; Dendritic Spines; Hist

2020
SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class.
    Neurochemical research, 2021, Volume: 46, Issue:5

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Cognitive Dysfunction; Depression; Female; Fluoxet

2021
NLRP3 inflammasome inhibition by histone acetylation ameliorates sevoflurane-induced cognitive impairment in aged mice by activating the autophagy pathway.
    Brain research bulletin, 2021, Volume: 172

    Topics: Acetylation; Aging; Animals; Autophagy; Cognitive Dysfunction; Hippocampus; Histone Deacetylase Inhi

2021
Treatment with Histone Deacetylase Inhibitor Attenuates Peripheral Inflammation-Induced Cognitive Dysfunction and Microglial Activation: The Effect of SAHA as a Peripheral HDAC Inhibitor.
    Neurochemical research, 2021, Volume: 46, Issue:9

    Topics: Animals; Cognitive Dysfunction; Cytokines; Hippocampus; Histone Deacetylase Inhibitors; Inflammation

2021
Suberoylanilide hydroxamic acid reversed cognitive and synaptic plasticity impairments induced by sevoflurane exposure in adult mice.
    Neuroreport, 2019, 03-06, Volume: 30, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Cognition; Cognitive Dysfunction; Histone Deacetylase Inhibitors;

2019