vorinostat has been researched along with Cognitive Dysfunction in 7 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.
Excerpt | Relevance | Reference |
---|---|---|
"Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental diseases associated with various gene mutations." | 1.62 | Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model. ( Aljazi, MB; Gao, Y; He, J; Wu, Y, 2021) |
"Depression is a disabling psychiatric disorder affecting millions of people all around the world." | 1.62 | SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class. ( Amini-Khoei, H; Dehpour, AR; Ershadi, ASB; Hosseini, MJ, 2021) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 6 (85.71) | 2.80 |
Authors | Studies |
---|---|
Kaur, N | 1 |
Fang, YC | 1 |
Lee, HY | 1 |
Singh, A | 1 |
Nepali, K | 1 |
Lin, MH | 1 |
Yeh, TK | 1 |
Lai, MJ | 1 |
Chan, L | 1 |
Tu, YK | 1 |
Banerjee, S | 1 |
Hu, CJ | 1 |
Liou, JP | 1 |
Gao, Y | 1 |
Aljazi, MB | 1 |
Wu, Y | 1 |
He, J | 1 |
Luo, F | 1 |
Min, J | 1 |
Wu, J | 1 |
Zuo, Z | 1 |
Ershadi, ASB | 1 |
Amini-Khoei, H | 1 |
Hosseini, MJ | 1 |
Dehpour, AR | 1 |
Fang, P | 1 |
Chen, C | 1 |
Zheng, F | 1 |
Jia, J | 1 |
Chen, T | 1 |
Zhu, J | 1 |
Chang, J | 1 |
Zhang, Z | 1 |
Takada, N | 1 |
Nakamura, Y | 1 |
Ikeda, K | 1 |
Takaoka, N | 1 |
Hisaoka-Nakashima, K | 1 |
Sanoh, S | 1 |
Kotake, Y | 1 |
Nakata, Y | 1 |
Morioka, N | 1 |
Zhang, D | 1 |
Xue, B | 1 |
You, J | 1 |
Zhang, B | 1 |
Chai, G | 1 |
7 other studies available for vorinostat and Cognitive Dysfunction
Article | Year |
---|---|
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment.
Topics: Animals; Azepines; Cell Line, Tumor; Clomipramine; Cognitive Dysfunction; Dementia, Vascular; Dose-R | 2020 |
Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model.
Topics: Animals; Autism Spectrum Disorder; Cognitive Dysfunction; Disease Models, Animal; DNA-Binding Protei | 2021 |
Histone Deacetylases May Mediate Surgery-Induced Impairment of Learning, Memory, and Dendritic Development.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Dendrites; Dendritic Spines; Hist | 2020 |
SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cognitive Dysfunction; Depression; Female; Fluoxet | 2021 |
NLRP3 inflammasome inhibition by histone acetylation ameliorates sevoflurane-induced cognitive impairment in aged mice by activating the autophagy pathway.
Topics: Acetylation; Aging; Animals; Autophagy; Cognitive Dysfunction; Hippocampus; Histone Deacetylase Inhi | 2021 |
Treatment with Histone Deacetylase Inhibitor Attenuates Peripheral Inflammation-Induced Cognitive Dysfunction and Microglial Activation: The Effect of SAHA as a Peripheral HDAC Inhibitor.
Topics: Animals; Cognitive Dysfunction; Cytokines; Hippocampus; Histone Deacetylase Inhibitors; Inflammation | 2021 |
Suberoylanilide hydroxamic acid reversed cognitive and synaptic plasticity impairments induced by sevoflurane exposure in adult mice.
Topics: Anesthetics, Inhalation; Animals; Cognition; Cognitive Dysfunction; Histone Deacetylase Inhibitors; | 2019 |