vorinostat has been researched along with Cognitive Dysfunction in 7 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental diseases associated with various gene mutations." | 1.62 | Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model. ( Aljazi, MB; Gao, Y; He, J; Wu, Y, 2021) |
| "Depression is a disabling psychiatric disorder affecting millions of people all around the world." | 1.62 | SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class. ( Amini-Khoei, H; Dehpour, AR; Ershadi, ASB; Hosseini, MJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 6 (85.71) | 2.80 |
| Authors | Studies |
|---|---|
| Kaur, N | 1 |
| Fang, YC | 1 |
| Lee, HY | 1 |
| Singh, A | 1 |
| Nepali, K | 1 |
| Lin, MH | 1 |
| Yeh, TK | 1 |
| Lai, MJ | 1 |
| Chan, L | 1 |
| Tu, YK | 1 |
| Banerjee, S | 1 |
| Hu, CJ | 1 |
| Liou, JP | 1 |
| Gao, Y | 1 |
| Aljazi, MB | 1 |
| Wu, Y | 1 |
| He, J | 1 |
| Luo, F | 1 |
| Min, J | 1 |
| Wu, J | 1 |
| Zuo, Z | 1 |
| Ershadi, ASB | 1 |
| Amini-Khoei, H | 1 |
| Hosseini, MJ | 1 |
| Dehpour, AR | 1 |
| Fang, P | 1 |
| Chen, C | 1 |
| Zheng, F | 1 |
| Jia, J | 1 |
| Chen, T | 1 |
| Zhu, J | 1 |
| Chang, J | 1 |
| Zhang, Z | 1 |
| Takada, N | 1 |
| Nakamura, Y | 1 |
| Ikeda, K | 1 |
| Takaoka, N | 1 |
| Hisaoka-Nakashima, K | 1 |
| Sanoh, S | 1 |
| Kotake, Y | 1 |
| Nakata, Y | 1 |
| Morioka, N | 1 |
| Zhang, D | 1 |
| Xue, B | 1 |
| You, J | 1 |
| Zhang, B | 1 |
| Chai, G | 1 |
7 other studies available for vorinostat and Cognitive Dysfunction
| Article | Year |
|---|---|
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment.
Topics: Animals; Azepines; Cell Line, Tumor; Clomipramine; Cognitive Dysfunction; Dementia, Vascular; Dose-R | 2020 |
Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model.
Topics: Animals; Autism Spectrum Disorder; Cognitive Dysfunction; Disease Models, Animal; DNA-Binding Protei | 2021 |
Histone Deacetylases May Mediate Surgery-Induced Impairment of Learning, Memory, and Dendritic Development.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Dendrites; Dendritic Spines; Hist | 2020 |
SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cognitive Dysfunction; Depression; Female; Fluoxet | 2021 |
NLRP3 inflammasome inhibition by histone acetylation ameliorates sevoflurane-induced cognitive impairment in aged mice by activating the autophagy pathway.
Topics: Acetylation; Aging; Animals; Autophagy; Cognitive Dysfunction; Hippocampus; Histone Deacetylase Inhi | 2021 |
Treatment with Histone Deacetylase Inhibitor Attenuates Peripheral Inflammation-Induced Cognitive Dysfunction and Microglial Activation: The Effect of SAHA as a Peripheral HDAC Inhibitor.
Topics: Animals; Cognitive Dysfunction; Cytokines; Hippocampus; Histone Deacetylase Inhibitors; Inflammation | 2021 |
Suberoylanilide hydroxamic acid reversed cognitive and synaptic plasticity impairments induced by sevoflurane exposure in adult mice.
Topics: Anesthetics, Inhalation; Animals; Cognition; Cognitive Dysfunction; Histone Deacetylase Inhibitors; | 2019 |