vorinostat has been researched along with Canine Diseases in 4 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "longicornis), and causes canine babesiosis." | 1.91 | In vitro screening of compounds from the Food and Drug Administration-approved library identifies anti-Babesia gibsoni activity of idarubicin hydrochloride and vorinostat. ( Amer, MM; Do, T; Galon, EM; Ji, S; Li, H; Liu, M; Ma, Y; Ma, Z; Xuan, X; Zafar, I, 2023) |
| "To determine whether exposure of canine cancer cells to histone deacetylase (HDAC) inhibitors S(+)-N-hydroxy-4-(3-methyl-2-phenyl-butyrylamino)benzamide (OSU-HDAC42) or suberoylanilide hydroxamic acid (SAHA) results in increased histone acetylation and decreased cell viability and whether any changes in viability involve induction of apoptosis or alterations in progression of the cell cycle." | 1.35 | Evaluation of the effects of histone deacetylase inhibitors on cells from canine cancer cell lines. ( Chen, CS; Kisseberth, WC; Kulp, SK; London, CA; Murahari, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suzuki, T | 1 |
| Aoshima, K | 1 |
| Yamazaki, J | 1 |
| Kobayashi, A | 1 |
| Kimura, T | 1 |
| Li, H | 1 |
| Galon, EM | 1 |
| Ji, S | 1 |
| Zafar, I | 1 |
| Ma, Z | 1 |
| Do, T | 1 |
| Amer, MM | 1 |
| Ma, Y | 1 |
| Liu, M | 1 |
| Xuan, X | 1 |
| Oyamada, T | 1 |
| Okano, S | 1 |
| Kisseberth, WC | 1 |
| Murahari, S | 1 |
| London, CA | 1 |
| Kulp, SK | 1 |
| Chen, CS | 1 |
4 other studies available for vorinostat and Canine Diseases
| Article | Year |
|---|---|
Manipulating histone acetylation leads to antitumor effects in hemangiosarcoma cells.
Topics: Acetylation; Animals; Apoptosis; Cell Line, Tumor; Dog Diseases; Dogs; Endothelial Cells; Hemangiosa | 2022 |
In vitro screening of compounds from the Food and Drug Administration-approved library identifies anti-Babesia gibsoni activity of idarubicin hydrochloride and vorinostat.
Topics: Animals; Babesia; Babesiosis; Dog Diseases; Dogs; Idarubicin; Ixodidae; United States; United States | 2023 |
Effect of suberoylanilide hydroxamic acid on peripheral blood mononuclear cell cytotoxicity towards tumor cells in canines.
Topics: Animals; Cell Line, Tumor; Cell Survival; Dog Diseases; Dogs; Gene Expression Regulation, Neoplastic | 2021 |
Evaluation of the effects of histone deacetylase inhibitors on cells from canine cancer cell lines.
Topics: Acetylation; Animals; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA | 2008 |