vorinostat has been researched along with Cancer of the Retina in 2 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vorinostat has demonstrated significant anticancer activity against hematologic and solid tumors at doses well tolerated by patients and has been approved for the treatment of patients with cutaneous T-cell lymphoma." | 1.35 | Molecular sequelae of histone deacetylase inhibition in human retinoblastoma cell lines: clinical implications. ( Kotoula, V; Marks, PA; McMullan, C; Miller, JW; Mitsiades, CS; Mitsiades, N; Negri, J; Poulaki, V, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poulaki, V | 1 |
| Mitsiades, CS | 1 |
| Kotoula, V | 1 |
| Negri, J | 1 |
| McMullan, C | 1 |
| Miller, JW | 1 |
| Marks, PA | 1 |
| Mitsiades, N | 1 |
| Dalgard, CL | 1 |
| Van Quill, KR | 1 |
| O'Brien, JM | 1 |
2 other studies available for vorinostat and Cancer of the Retina
| Article | Year |
|---|---|
Molecular sequelae of histone deacetylase inhibition in human retinoblastoma cell lines: clinical implications.
Topics: Acetylation; Apoptosis; Bromodeoxyuridine; Caspases; Cell Line, Tumor; Cell Proliferation; Cinnamate | 2009 |
Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Benzamides; Blotting, Western; Caspase 3; Cas | 2008 |