vorinostat has been researched along with Bowel Diseases, Inflammatory in 4 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflammatory bowel diseases are multifactorial, chronic, continuous, relapsing, and immune-mediated diseases of the gastrointestinal tract." | 1.91 | Epigenetics of Inflammatory Bowel Diseases. ( Törüner, M; Ünal, NG, 2023) |
| "Givinostat treatment mediated an accelerated wound closure in scratch assays." | 1.51 | HDAC inhibitors promote intestinal epithelial regeneration via autocrine TGFβ1 signalling in inflammation. ( Friedrich, M; Gerbeth, L; Gerling, M; Glauben, R; Keye, J; Rosenthal, R; Schmidt, F; Siegmund, B; Steiger, K; Weichert, W; Weidinger, C; Wu, H, 2019) |
| "MMR-deficient colorectal cancers are classically characterized by right-sided location, multifocality, mucinous histology, and lymphocytic infiltration." | 1.35 | Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer. ( Afrasiabi, K; Birnbaumer, L; Edwards, RA; Lipkin, SM; Pham, T; Wang, K; Witherspoon, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Törüner, M | 1 |
| Ünal, NG | 1 |
| Wetzel, A | 1 |
| Scholtka, B | 1 |
| Gerecke, C | 1 |
| Kleuser, B | 1 |
| Friedrich, M | 1 |
| Gerbeth, L | 1 |
| Gerling, M | 1 |
| Rosenthal, R | 1 |
| Steiger, K | 1 |
| Weidinger, C | 1 |
| Keye, J | 1 |
| Wu, H | 1 |
| Schmidt, F | 1 |
| Weichert, W | 1 |
| Siegmund, B | 1 |
| Glauben, R | 1 |
| Edwards, RA | 1 |
| Witherspoon, M | 1 |
| Wang, K | 1 |
| Afrasiabi, K | 1 |
| Pham, T | 1 |
| Birnbaumer, L | 1 |
| Lipkin, SM | 1 |
4 other studies available for vorinostat and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
Epigenetics of Inflammatory Bowel Diseases.
Topics: Animals; DNA Methylation; Epigenesis, Genetic; Histones; Inflammatory Bowel Diseases; Mice; MicroRNA | 2023 |
Epigenetic histone modulation contributes to improvements in inflammatory bowel disease via EBI3.
Topics: Animals; Caspase 3; CD3 Complex; Colitis; Dextran Sulfate; Epigenesis, Genetic; Histone Deacetylase | 2020 |
HDAC inhibitors promote intestinal epithelial regeneration via autocrine TGFβ1 signalling in inflammation.
Topics: Animals; Autocrine Communication; Carbamates; Cells, Cultured; Colitis; Disease Models, Animal; Elec | 2019 |
Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.
Topics: Adaptor Proteins, Signal Transducing; Adenoma; Adenosine Triphosphatases; Animals; Cell Hypoxia; Col | 2009 |