vorinostat has been researched along with Benign Cerebellar Neoplasms in 7 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Medulloblastoma is a malignant pediatric brain tumor." | 1.38 | REST is a novel prognostic factor and therapeutic target for medulloblastoma. ( Cooper, L; Fangusaro, J; Goldman, S; Gopalakrishnan, V; Hasselblatt, M; Helenowski, IB; Laureano, A; MacDonald, T; Rajaram, V; Riedemann, L; Taylor, P, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Leary, SES | 1 |
| Kilburn, L | 1 |
| Geyer, JR | 1 |
| Kocak, M | 1 |
| Huang, J | 1 |
| Smith, KS | 1 |
| Hadley, J | 1 |
| Ermoian, R | 1 |
| MacDonald, TJ | 1 |
| Goldman, S | 2 |
| Phillips, P | 1 |
| Young Poussaint, T | 1 |
| Olson, JM | 3 |
| Ellison, DW | 1 |
| Dunkel, IJ | 1 |
| Fouladi, M | 1 |
| Onar-Thomas, A | 1 |
| Northcott, PA | 1 |
| Patties, I | 1 |
| Kortmann, RD | 1 |
| Menzel, F | 1 |
| Glasow, A | 1 |
| Häcker, S | 1 |
| Dittrich, A | 1 |
| Mohr, A | 1 |
| Schweitzer, T | 1 |
| Rutkowski, S | 1 |
| Krauss, J | 1 |
| Debatin, KM | 1 |
| Fulda, S | 1 |
| Canettieri, G | 1 |
| Di Marcotullio, L | 1 |
| Coni, S | 1 |
| Greco, A | 1 |
| Gulino, A | 1 |
| Taylor, P | 1 |
| Fangusaro, J | 1 |
| Rajaram, V | 1 |
| Helenowski, IB | 1 |
| MacDonald, T | 1 |
| Hasselblatt, M | 1 |
| Riedemann, L | 1 |
| Laureano, A | 1 |
| Cooper, L | 1 |
| Gopalakrishnan, V | 1 |
| Spiller, SE | 2 |
| Ravanpay, AC | 1 |
| Hahn, AW | 1 |
| Ditzler, SH | 1 |
| Pullar, BJ | 1 |
1 trial available for vorinostat and Benign Cerebellar Neoplasms
| Article | Year |
|---|---|
Vorinostat and isotretinoin with chemotherapy in young children with embryonal brain tumors: A report from the Pediatric Brain Tumor Consortium (PBTC-026).
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, | 2022 |
6 other studies available for vorinostat and Benign Cerebellar Neoplasms
| Article | Year |
|---|---|
Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Di | 2016 |
Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8.
Topics: Benzamides; Caspase 8; Cell Line, Tumor; Cell Survival; Cerebellar Neoplasms; Drug Combinations; Dru | 2009 |
Turning off the switch in medulloblastoma: the inhibitory acetylation of an oncogene.
Topics: Acetylation; Cerebellar Neoplasms; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hyd | 2010 |
REST is a novel prognostic factor and therapeutic target for medulloblastoma.
Topics: Adolescent; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cereb | 2012 |
Suberoylanilide hydroxamic acid is effective in preclinical studies of medulloblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cells, Cultured; Cerebellar Neoplasms; Child; Fibroblasts | 2006 |
Response of preclinical medulloblastoma models to combination therapy with 13-cis retinoic acid and suberoylanilide hydroxamic acid (SAHA).
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Morphogenetic Protein 2; Bo | 2008 |