vorinostat has been researched along with Arthritis, Rheumatoid in 5 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Furthermore, compared with SAHA, MPT0G009 exhibited longer half-life (9." | 1.40 | Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009. ( Hsieh, IN; Lai, MJ; Lee, HY; Li, YH; Liou, JP; Yang, CR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, DS | 1 |
| Min, HK | 1 |
| Kim, EK | 1 |
| Yang, SC | 1 |
| Na, HS | 1 |
| Lee, SY | 1 |
| Choi, JW | 1 |
| Jung, KA | 1 |
| Kwok, SK | 1 |
| Park, SH | 1 |
| Cho, ML | 1 |
| Hsieh, IN | 1 |
| Liou, JP | 1 |
| Lee, HY | 1 |
| Lai, MJ | 1 |
| Li, YH | 1 |
| Yang, CR | 1 |
| Chen, H | 1 |
| Pan, J | 1 |
| Wang, JD | 1 |
| Liao, QM | 1 |
| Xia, XR | 1 |
| Choo, QY | 1 |
| Ho, PC | 1 |
| Tanaka, Y | 1 |
| Lin, HS | 2 |
| Hu, CY | 1 |
| Chan, HY | 1 |
| Liew, YY | 1 |
| Huang, HP | 1 |
| Lepescheux, L | 1 |
| Bastianelli, E | 1 |
| Baron, R | 1 |
| Rawadi, G | 1 |
| Clément-Lacroix, P | 1 |
5 other studies available for vorinostat and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Suberoylanilide Hydroxamic Acid Attenuates Autoimmune Arthritis by Suppressing Th17 Cells through NR1D1 Inhibition.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Autoimmune Diseases; | 2019 |
Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009.
Topics: Acetylation; Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthr | 2014 |
Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
Topics: Acetylcysteine; Apoptosis; Arthritis, Rheumatoid; bcl-X Protein; Caspase 3; Cell Survival; Cells, Cu | 2016 |
Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipopolysaccharide-stimulated NF-kappaB p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic E11 cells.
Topics: Animals; Arthritis, Rheumatoid; Benzamides; Cells, Cultured; Cytokines; Down-Regulation; Fibroblasts | 2010 |
Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzamides; Female; H | 2007 |