vorinostat has been researched along with Arthritis, Degenerative in 4 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhong, HM | 1 |
| Ding, QH | 1 |
| Chen, WP | 1 |
| Luo, RB | 1 |
| Wang, JH | 1 |
| Shih, KS | 1 |
| Wu, YW | 1 |
| Wang, AW | 1 |
| Yang, CR | 1 |
| Makki, MS | 2 |
| Haqqi, TM | 2 |
4 other studies available for vorinostat and Arthritis, Degenerative
| Article | Year |
|---|---|
Vorinostat, a HDAC inhibitor, showed anti-osteoarthritic activities through inhibition of iNOS and MMP expression, p38 and ERK phosphorylation and blocking NF-κB nuclear translocation.
Topics: Active Transport, Cell Nucleus; Aged; Cell Nucleus; Cells, Cultured; Chondrocytes; Extracellular Sig | 2013 |
Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes.
Topics: Case-Control Studies; Cells, Cultured; Fibroblasts; Gene Expression; Histone Deacetylase Inhibitors; | 2013 |
Histone deacetylase inhibitor vorinostat (SAHA, MK0683) perturb miR-9-MCPIP1 axis to block IL-1β-induced IL-6 expression in human OA chondrocytes.
Topics: Adult; Aged; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Chondrocytes; Female; Gene Expression | 2017 |
Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte.
Topics: Aged; Blotting, Western; Cartilage, Articular; Chondrocytes; Collagen Type II; Down-Regulation; Fema | 2016 |