vorinostat has been researched along with Androgen-Independent Prostatic Cancer in 4 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Platinum-based drugs have been used in multiple clinical trials as monotherapy or in combination with other chemotherapeutic agents for the treatment of CRPC." | 1.91 | Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH. ( Chang, T; Lian, Z; Liang, Z; Liu, R; Ma, S; Ma, X; Wang, Y; Wen, X, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, T | 1 |
| Lian, Z | 1 |
| Ma, S | 1 |
| Liang, Z | 1 |
| Ma, X | 1 |
| Wen, X | 1 |
| Wang, Y | 1 |
| Liu, R | 1 |
| Park, SE | 1 |
| Kim, HG | 1 |
| Kim, DE | 1 |
| Jung, YJ | 1 |
| Kim, Y | 1 |
| Jeong, SY | 1 |
| Choi, EK | 1 |
| Hwang, JJ | 1 |
| Kim, CS | 1 |
| McLeod, AB | 1 |
| Stice, JP | 1 |
| Wardell, SE | 1 |
| Alley, HM | 1 |
| Chang, CY | 1 |
| McDonnell, DP | 1 |
| Rosati, R | 1 |
| Chen, B | 1 |
| Patki, M | 1 |
| McFall, T | 1 |
| Ou, S | 1 |
| Heath, E | 1 |
| Ratnam, M | 1 |
| Qin, Z | 1 |
4 other studies available for vorinostat and Androgen-Independent Prostatic Cancer