vorinostat has been researched along with Alloxan Diabetes in 3 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "One of the earliest features of diabetic nephropathy is renal enlargement." | 1.37 | Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor. ( Advani, A; Advani, SL; Connelly, KA; Gilbert, RE; Huang, Q; Lee, K; Thai, K; Yuen, DA, 2011) |
| "Vorinostat treatment had no effect on albuminuria, glomerular collagen IV concentration, or mesangiolysis in diabetic mice genetically deficient in eNOS." | 1.37 | Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism. ( Advani, A; Advani, SL; Connelly, KA; Gilbert, RE; Huang, Q; Kelly, DJ; Marsden, PA; Thai, K; White, KE; Yuen, DA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bocchi, L | 1 |
| Motta, BM | 1 |
| Savi, M | 1 |
| Vilella, R | 1 |
| Meraviglia, V | 1 |
| Rizzi, F | 1 |
| Galati, S | 1 |
| Buschini, A | 1 |
| Lazzaretti, M | 1 |
| Pramstaller, PP | 1 |
| Rossini, A | 1 |
| Stilli, D | 1 |
| Gilbert, RE | 2 |
| Huang, Q | 2 |
| Thai, K | 2 |
| Advani, SL | 2 |
| Lee, K | 1 |
| Yuen, DA | 2 |
| Connelly, KA | 2 |
| Advani, A | 2 |
| White, KE | 1 |
| Kelly, DJ | 1 |
| Marsden, PA | 1 |
3 other studies available for vorinostat and Alloxan Diabetes
| Article | Year |
|---|---|
The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Restores Cardiomyocyte Contractility in a Rat Model of Early Diabetes.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Diabetes Mellitus, Experimental; Histone | 2019 |
Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor.
Topics: Analysis of Variance; Animals; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Experimental; | 2011 |
Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism.
Topics: Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Histone Deacety | 2011 |