Page last updated: 2024-11-04

vorinostat and Allodynia

vorinostat has been researched along with Allodynia in 9 studies

Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Research Excerpts

ExcerptRelevanceReference
" Here we explored the impact of the histone deacetylase (HDAC) inhibitor suberoylanilide hydroxamic acid (SAHA) on somatic hyperalgesia induced by stress or stress combined with orofacial inflammation, which mimicked the comorbidity of FMS and TMD in rats."1.72SAHA Inhibits Somatic Hyperalgesia Induced by Stress Combined with Orofacial Inflammation Through Targeting Different Spinal 5-HT Receptor Subtypes. ( Bai, G; Cao, DY; Li, JF; Qiu, XY; Tao, ZY; Wei, SQ, 2022)
"Furthermore, this hyperalgesia was attenuated by the histone deacetylase inhibitor, suberoylanilide hydroxamic acid treatment."1.51Effect of Histone Deacetylase Inhibitor on Ethanol Withdrawal-Induced Hyperalgesia in Rats. ( Akbari, A; Pandey, SC; Pradhan, AA; Tipton, AF; Zhang, H, 2019)
"The long term use of opioids for the treatment of pain leads to a group of maladaptations which includes opioid-induced hyperalgesia (OIH)."1.40Epigenetic regulation of spinal cord gene expression controls opioid-induced hyperalgesia. ( Clark, JD; Liang, DY; Sahbaie, P; Shi, XY; Sun, Y, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Tao, ZY1
Qiu, XY1
Wei, SQ1
Bai, G2
Li, JF1
Cao, DY2
Wang, C1
Chen, R1
Zhu, X1
Zhang, X1
Pradhan, AA1
Tipton, AF1
Zhang, H2
Akbari, A1
Pandey, SC1
Sun, Y2
Sahbaie, P2
Liang, DY3
Li, WW1
Li, XQ1
Shi, XY2
Clark, JD3
Moloney, RD1
Stilling, RM1
Dinan, TG1
Cryan, JF1
Cui, SS1
Lu, R1
Wang, W1
Ke, JJ1
Ji, Y1
Karpowicz, JM1
Traub, RJ1
Li, X1

Other Studies

9 other studies available for vorinostat and Allodynia

ArticleYear
SAHA Inhibits Somatic Hyperalgesia Induced by Stress Combined with Orofacial Inflammation Through Targeting Different Spinal 5-HT Receptor Subtypes.
    Neurochemical research, 2022, Volume: 47, Issue:5

    Topics: Animals; Epigenesis, Genetic; Female; Hyperalgesia; Inflammation; Rats; Rats, Sprague-Dawley; Recept

2022
Suberoylanilide Hydroxamic Acid Ameliorates Pain Sensitization in Central Neuropathic Pain After Spinal Cord Injury via the HDAC5/NEDD4/SCN9A Axis.
    Neurochemical research, 2023, Volume: 48, Issue:8

    Topics: Animals; Hyperalgesia; Mice; Neuralgia; Spinal Cord; Spinal Cord Injuries; Up-Regulation; Vorinostat

2023
Effect of Histone Deacetylase Inhibitor on Ethanol Withdrawal-Induced Hyperalgesia in Rats.
    The international journal of neuropsychopharmacology, 2019, 08-01, Volume: 22, Issue:8

    Topics: Analgesics; Animals; Behavior, Animal; Ethanol; Histone Deacetylase Inhibitors; Hyperalgesia; Male;

2019
Epigenetic regulation of spinal CXCR2 signaling in incisional hypersensitivity in mice.
    Anesthesiology, 2013, Volume: 119, Issue:5

    Topics: Anacardic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Chromatin Immu

2013
Epigenetic regulation of spinal cord gene expression controls opioid-induced hyperalgesia.
    Molecular pain, 2014, Sep-12, Volume: 10

    Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Azepines; Benzamides; Brain-Derived Neurotrophic

2014
Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition.
    Neurogastroenterology and motility, 2015, Volume: 27, Issue:12

    Topics: Animals; Anxiety; Blotting, Western; Disease Models, Animal; Female; Histone Deacetylase Inhibitors;

2015
Suberoylanilide hydroxamic acid prevents downregulation of spinal glutamate transporter-1 and attenuates spinal nerve ligation-induced neuropathic pain behavior.
    Neuroreport, 2016, Apr-13, Volume: 27, Issue:6

    Topics: Acetylation; Animals; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 2;

2016
EXPRESS: Histone hyperacetylation modulates spinal type II metabotropic glutamate receptor alleviating stress-induced visceral hypersensitivity in female rats.
    Molecular pain, 2016, Volume: 12

    Topics: Acetylation; Amino Acids; Animals; Chromatin Immunoprecipitation; Female; Histone Deacetylase Inhibi

2016
Epigenetic regulation of opioid-induced hyperalgesia, dependence, and tolerance in mice.
    The journal of pain, 2013, Volume: 14, Issue:1

    Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Blotting, We

2013