vorinostat has been researched along with Age-Related Memory Disorders in 5 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin resistance has been reported as a strong risk factor for Alzheimer's disease." | 1.43 | Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice. ( Sharma, S; Taliyan, R, 2016) |
| "Sepsis-associated encephalopathy (SAE), which associates with neuronal apoptosis and cognitive disorders, is a common complication of systemic sepsis." | 1.40 | Epigenetic modulation of neuronal apoptosis and cognitive functions in sepsis-associated encephalopathy. ( Cai, S; Fang, J; Lian, Y; Wen, P; Xie, K, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, XY | 1 |
| Liu, XW | 1 |
| Wang, J | 1 |
| Luo, F | 1 |
| Min, J | 1 |
| Wu, J | 1 |
| Zuo, Z | 1 |
| Fang, J | 1 |
| Lian, Y | 1 |
| Xie, K | 1 |
| Cai, S | 1 |
| Wen, P | 1 |
| Lin, XF | 1 |
| Han, YQ | 1 |
| Li, HL | 1 |
| Zhao, YP | 1 |
| Fei, XJ | 1 |
| Sheng, JX | 1 |
| Lu, HH | 1 |
| Liu, S | 1 |
| Zhang, L | 1 |
| Sharma, S | 1 |
| Taliyan, R | 1 |
5 other studies available for vorinostat and Age-Related Memory Disorders
| Article | Year |
|---|---|
Suberoylanilide hydroxamic acid (SAHA) attenuates memory impairment in the offspring of rats exposed to sevoflurane anesthesia.
Topics: Anesthesia; Animals; Female; Hippocampus; Learning; Memory Disorders; MicroRNAs; Pregnancy; Rats; Se | 2023 |
Histone Deacetylases May Mediate Surgery-Induced Impairment of Learning, Memory, and Dendritic Development.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Dendrites; Dendritic Spines; Hist | 2020 |
Epigenetic modulation of neuronal apoptosis and cognitive functions in sepsis-associated encephalopathy.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Brain Diseases; Cells, Cultured; Cogn | 2014 |
SAHA attenuates sevoflurane-induced learning and memory impairments in fetal mice.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Histone Deacetylase Inhibitors; Hydroxamic Acids | 2014 |
Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognition Disorder | 2016 |