Page last updated: 2024-11-04

vorinostat and Adenoma

vorinostat has been researched along with Adenoma in 4 studies

Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"MMR-deficient colorectal cancers are classically characterized by right-sided location, multifocality, mucinous histology, and lymphocytic infiltration."1.35Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer. ( Afrasiabi, K; Birnbaumer, L; Edwards, RA; Lipkin, SM; Pham, T; Wang, K; Witherspoon, M, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, J1
Chatain, GP1
Bugarini, A1
Wang, X1
Maric, D1
Walbridge, S1
Zhuang, Z1
Chittiboina, P1
Fatemi, M1
Paul, TA1
Brodeur, GM1
Shokrani, B1
Brim, H1
Ashktorab, H1
Sangeetha, SR1
Singh, N1
Vender, JR1
Dhandapani, KM1
Edwards, RA1
Witherspoon, M1
Wang, K1
Afrasiabi, K1
Pham, T1
Birnbaumer, L1
Lipkin, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation and Treatment of Neurosurgical Disorders[NCT00060541]5,000 participants (Anticipated)Observational2003-06-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for vorinostat and Adenoma

ArticleYear
Histone Deacetylase Inhibitor SAHA Is a Promising Treatment of Cushing Disease.
    The Journal of clinical endocrinology and metabolism, 2017, 08-01, Volume: 102, Issue:8

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenocorticotropic Hormone; Animals; Apoptosis; Blotting

2017
Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages.
    Cancer, 2014, Jan-15, Volume: 120, Issue:2

    Topics: Adenoma; Azacitidine; Black or African American; Cell Line, Tumor; Cell Movement; Cell Proliferation

2014
Suberoylanilide hydroxamic acid (SAHA) induces growth arrest and apoptosis in pituitary adenoma cells.
    Endocrine, 2009, Volume: 35, Issue:3

    Topics: Adenoma; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Proliferation; Dose-R

2009
Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.
    Cancer research, 2009, Aug-15, Volume: 69, Issue:16

    Topics: Adaptor Proteins, Signal Transducing; Adenoma; Adenosine Triphosphatases; Animals; Cell Hypoxia; Col

2009