Page last updated: 2024-11-04

vorinostat and Acute Promyelocytic Leukemia

vorinostat has been researched along with Acute Promyelocytic Leukemia in 3 studies

Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Licht, JD1
He, LZ1
Tolentino, T1
Grayson, P1
Zhong, S1
Warrell, RP1
Rifkind, RA1
Marks, PA1
Richon, VM1
Pandolfi, PP1
Amin, HM1
Saeed, S1
Alkan, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
IGHID 11424 - A Pilot Trial of the Effect of Vorinostat and AGS-004 on Persistent HIV-1 Infection (The VOR VAX Study)[NCT02707900]Phase 16 participants (Actual)Interventional2016-03-31Terminated (stopped due to Manufacturing of the AGS-004 HIV vaccine by Argos could no longer be provided.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for vorinostat and Acute Promyelocytic Leukemia

ArticleYear
Targeting aberrant transcriptional repression in leukemia: a therapeutic reality?
    The Journal of clinical investigation, 2001, Volume: 108, Issue:9

    Topics: Cell Adhesion; Enzyme Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Leukemia, Promyelo

2001
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Northern; Blotting, Western; Cell Cycle; Cell D

2001
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17).
    British journal of haematology, 2001, Volume: 115, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Antineoplastic Agents; Apoptosis; Butyrates; Carr

2001