vlx600 has been researched along with Carcinoma--Ovarian-Epithelial* in 1 studies
1 other study(ies) available for vlx600 and Carcinoma--Ovarian-Epithelial
Article | Year |
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BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents.
BRCA1 plays a key role in homologous recombination (HR) DNA repair. Accordingly, changes that downregulate BRCA1, including Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cyclin-Dependent Kinases; DNA Methylation; Energy Metabolism; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrazones; Hydroxybenzoates; Mice; Mitochondria; Mutation; Nicotinamide N-Methyltransferase; Ovarian Neoplasms; Ovary; Oxidative Phosphorylation; Promoter Regions, Genetic; Tigecycline; Triazoles; Up-Regulation; Xenograft Model Antitumor Assays | 2019 |