vitamin-k-semiquinone-radical and Lung-Diseases--Interstitial

Numerous studies have shown that perioperative heparin bridging in patients treated with a vitamin K antagonist leads to an increased incidence of bleeding and so far, there is no evidence that it leads to a significant reduction in postoperative thromboembolism as summarised in this review. Prophylactic dosage of heparin is recommended after major surgery. Heparin bridging is not relevant in patients receiving a direct oral anticoagulant due to the rapid onset and offset of action of DOACs.

Topics: Anticoagulants; Heparin; Humans; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Vitamin K

Topics: Aged; Anticoagulants; Antitubercular Agents; Comorbidity; Cyclosporine; Drug Substitution; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Humans; Immunosuppressive Agents; Kidney Transplantation; Lung Diseases, Interstitial; Pericarditis; Phenindione; Polypharmacy; Postoperative Complications; Rifampin; Sirolimus; Venous Thrombosis; Vitamin K

Topics: Antifibrinolytic Agents; Benzoates; Child; Humans; Infant; Lung Diseases, Interstitial; Pneumonia; Retinoids; Vitamin K