vitamin-k-semiquinone-radical and Jaundice

Topics: Adult; Altitude; Bilirubin; Biological Transport; Erythrocyte Aging; Female; Hemolysis; Hepatitis B; Hexosyltransferases; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infant, Newborn; Jaundice; Liver; Novobiocin; Portacaval Shunt, Surgical; Pregnancy; Vitamin K

Topics: Bilirubin; Cholestyramine Resin; Diagnosis, Differential; Eclampsia; Female; Fetus; Hepatitis; Humans; Hyperemesis Gravidarum; Jaundice; Jaundice, Chronic Idiopathic; Liver Diseases; Pregnancy; Pregnancy Complications; Vitamin K

Topics: Alkaline Phosphatase; Bilirubin; Blood Chemical Analysis; Blood Proteins; Clinical Enzyme Tests; Clinical Laboratory Techniques; Diagnosis, Differential; Galactose; Jaundice; Liver Function Tests; Prothrombin; Radiography; Urine; Urobilinogen; Vitamin K

Topics: 4-Hydroxycoumarins; Aged; Drug Hypersensitivity; Drug Overdose; Female; Humans; Indenes; Jaundice; Urticaria; Vitamin K

The coagulation function in patients with pancreatic carcinoma is abnormal and the reason is not very clear. In this study, we retrospectively analyzed the coagulation function in patients with pancreatic carcinoma.. From June 2004 to December 2007, 132 patients received diagnosis and treatment in our hospital. The coagulative parameters including the prothrombin time, activated partial thromboplastin time, and fibrinogen levels were collected and studied retrospectively.. The average fibrinogen levels in patients with pancreatic carcinoma, (476.21 +/- 142.05) mg/dl, were significantly higher than in patients with cholangiolithiasis, (403.28 +/- 126.41) mg/dl (P < 0.05). In patients with pancreatic carcinoma, the levels of fibrinogen in the group with jaundice were significantly higher than in patients without jaundice (P < 0.05). In patients who received Pancreaticoduodenectomy, Whipple's operation, the level of fibrinogen in the group with local invasiveness was significantly higher than in the group without invasiveness. The group with lymphatic metastasis had higher levels than the group without lymphatic metastasis (P < 0.05). There was no significant difference of intraoperative blood loss between patients with vitamin K, (748.27 +/- 448.51) ml, and those without vitamin K, (767.31 +/- 547.89) ml (P > 0.05).. The level of fibrinogen in patients with pancreatic carcinoma was elevated. The elevated fibrinogen level may be associated with invasiveness and lymphatic metastasis. Using vitamin K in perioperation management did not reduce intraoperative blood loss.

Topics: Adult; Aged; Aged, 80 and over; Blood Coagulation; Cholelithiasis; Female; Fibrinogen; Humans; Jaundice; Lymphatic Metastasis; Male; Middle Aged; Pancreatic Neoplasms; Pancreaticoduodenectomy; Retrospective Studies; Vitamin K; Young Adult

Topics: Antineoplastic Agents; Cholestasis, Extrahepatic; Cohort Studies; Diagnosis, Differential; Follow-Up Studies; Hemangioma, Cavernous; Humans; Hydroxyurea; Jaundice; Male; Middle Aged; Portal Vein; Propranolol; Radiography, Abdominal; Retrospective Studies; Risk Factors; Time Factors; Tomography, X-Ray Computed; Vascular Neoplasms; Vasodilator Agents; Vitamin K

Presented is the case of a 19-year-old midshipman at the United States Naval Academy who developed heat stroke. After appropriate therapy and apparent resolution of the heat-related illness, the patient re-presented with jaundice and biochemical evidence of severe hepatitis. He improved with supportive care and was asymptomatic when discharged. The differential diagnosis and clinical course are described, and hepatic and metabolic effects of thermal injury are discussed.

Topics: Adult; Cryotherapy; Heat Exhaustion; Humans; Jaundice; Male; Vitamin K

A simple and rapid in vitro test was devised to detect the presence of the prothrombin precursor molecule circulating in the plasma of 55 out of 56 patients receiving oral vitamin K antagonists and in 4 out of 5 patients with obstructive jaundice, using either Dispholidus typus or Echis carinatus venoms. The absence of the molecule from the plasma of jaundiced patients was suggestive of hepatocellular rather than obstructive jaundice. The test is based on the clotting of aluminium hydroxide gel adsorbed plasma by the venoms. It is more sensitive and easier to perform than measuring antigenic prothrombin levels.

Topics: Adsorption; Cholestasis; Cholestasis, Intrahepatic; Diagnosis, Differential; Humans; Jaundice; Prothrombin; Prothrombin Time; Snake Venoms; Vitamin K

Topics: Aminobenzoates; Analgesics; Antitubercular Agents; Barbiturates; Chloral Hydrate; Glucuronosyltransferase; Hexosyltransferases; Humans; Hyperbilirubinemia, Hereditary; Jaundice; Nicotinic Acids; Phenols; Terpenes; Vitamin K

Topics: Bilirubin; Color; Copper; Diagnosis, Differential; Humans; Iron; Jaundice; Laparoscopy; Palpation; Skin; Transaminases; Vitamin K

Topics: Blood Coagulation Tests; Fibrinolysis; Humans; Jaundice; Thrombin; Thromboembolism; Vitamin K

Topics: Adult; Anesthesia, Spinal; Antibodies; Autoimmune Diseases; Blood Coagulation Tests; Blood Protein Electrophoresis; Dicumarol; Eosinophilia; Fibrinogen; Heparin; Humans; Jaundice; Male; Pneumonia; Priapism; Pulmonary Embolism; Steroids; Thrombophlebitis; Vitamin K

Topics: Blood Coagulation Disorders; Blood Transfusion; Chemical and Drug Induced Liver Injury; Hemorrhage; Hepatitis; Hepatitis A; Humans; Jaundice; Liver; Liver Diseases; Prothrombin Time; Surgical Procedures, Operative; Transplantation; Vitamin K

Topics: Bilirubin; Charcoal; Chloramphenicol; Drug Therapy; Exchange Transfusion, Whole Blood; Humans; Infant; Infant, Newborn; Jaundice; Jaundice, Neonatal; Kanamycin; Penicillins; Streptomycin; Therapeutics; Vitamin K

Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Diet; Diet Therapy; Hepatitis; Hepatitis A; Humans; Jaundice; Oxytetracycline; Pathology; Prednisone; Prognosis; Tetracycline; Therapeutics; Vitamin K; Vitamins

Topics: Alcoholism; Anemia; Anemia, Hypochromic; Avitaminosis; Cholestyramine Resin; Common Bile Duct; Diet; Diet Therapy; Diuretics; Folic Acid; Folic Acid Deficiency; Gastrointestinal Hemorrhage; Humans; Hydrochlorothiazide; Ion Exchange Resins; Jaundice; Liver Cirrhosis; Liver Cirrhosis, Biliary; Postoperative Complications; Prothrombin Time; Vitamin B 12; Vitamin B Complex; Vitamin K

Topics: Antifibrinolytic Agents; Chlorobutanol; Dehydration; Epidemiology; Hot Temperature; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice; Jaundice, Neonatal; Propylene Glycols; Toxicology; Vitamin K

Topics: Diagnosis, Differential; Female; Humans; Jaundice; Pregnancy; Pregnancy Complications; Prognosis; Vitamin K

Topics: Bilirubin; Blood Chemical Analysis; Erythrocytes; Heinz Bodies; Hematologic Tests; Hematology; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Jaundice; Jaundice, Neonatal; Plasma; Toxicology; Vitamin K

Topics: Analgesics; Analgesics, Non-Narcotic; Anemia; Anemia, Hemolytic; Antimalarials; Antipyretics; Erythroblastosis, Fetal; Female; Fetal Diseases; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice; Jaundice, Neonatal; Maternal-Fetal Exchange; North Carolina; Novobiocin; Pregnancy; Salicylates; Sulfisoxazole; Toxicology; Vitamin K

Topics: Anemia; Anemia, Hemolytic; Blood Chemical Analysis; Drug Therapy; Exchange Transfusion, Whole Blood; Genetics, Medical; Glucose; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Hemoglobinometry; Humans; Infant Mortality; Infant, Newborn; Jaundice; Jaundice, Neonatal; Kernicterus; Naphthalenes; Oxidoreductases; Phosphates; Toxicology; Vitamin K

Topics: Animals; Bilirubin; Hemoglobins; Hemolysis; Hyperbilirubinemia; Jaundice; Rats; Vitamin K

Topics: Antifibrinolytic Agents; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant, Newborn; Jaundice; Jaundice, Neonatal; Naphthoquinones; Nigeria; Vitamin K

Topics: Antifibrinolytic Agents; Female; Hemorrhage; Humans; Infant; Infant, Newborn; Jaundice; Jaundice, Neonatal; Maternal-Fetal Exchange; Mothers; Pregnancy; Preventive Medicine; Vitamin K; Vitamin K Deficiency Bleeding

Topics: Bilirubin; Blood Coagulation Tests; Female; Humans; Infant; Infant, Newborn; Jaundice; Jaundice, Neonatal; Liver Function Tests; Mothers; Postpartum Period; Pregnancy; Prothrombin; Umbilical Cord; Vitamin K

Topics: Bilirubin; Enzyme Inhibitors; Humans; Infant; Infant, Newborn; Jaundice; Liver; Novobiocin; Pharmacology; Progestins; Rats; Research; Transferases; Vitamin K

Topics: Bilirubin; Blood Chemical Analysis; Erythromycin; Exchange Transfusion, Whole Blood; Female; Humans; Infant, Newborn; Jaundice; Jaundice, Neonatal; Maternal-Fetal Exchange; Meperidine; Penicillins; Phenothiazines; Pregnancy; Toxicology; Vitamin K

Topics: Anemia, Hemolytic; Antimalarials; Brain Diseases; Cerebral Palsy; Chloramphenicol; Genetics, Medical; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Jaundice; Jaundice, Neonatal; Naphthalenes; Nitrofurantoin; Phenylhydrazines; Pregnancy; Quinidine; Sulfonamides; Thailand; Toxicology; Vitamin K

Topics: Antifibrinolytic Agents; Child; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice; Vitamin K

Topics: Bilirubin; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice; Mothers; Naphthoquinones; Vitamin K

Topics: Bilirubin; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Jaundice; Naphthoquinones; Retinoids; Vitamin K

Topics: Anemia; Anemia, Hemolytic; Child; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice; Vitamin K

Topics: Hemorrhage; Humans; Jaundice; Liver Diseases; Vitamin K

Topics: Antifibrinolytic Agents; Child; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice; Naphthoquinones; Vitamin K

Topics: Antifibrinolytic Agents; Bilirubin; Erythroblastosis, Fetal; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice; Kernicterus; Naphthoquinones; Vitamin K

Topics: Antifibrinolytic Agents; Factor Xa; Humans; Jaundice; Jaundice, Obstructive; Liver Cirrhosis; Naphthoquinones; Vitamin K; Vitamin K 1

Topics: Antifibrinolytic Agents; Bilirubin; Blood Circulation; Blood Coagulation; Heparin Antagonists; Humans; Jaundice; Vitamin K

Topics: Antifibrinolytic Agents; Blood Coagulation; Diagnosis, Differential; Humans; Jaundice; Liver; Liver Function Tests; Vitamin K

Topics: Antifibrinolytic Agents; Jaundice; Liver; Liver Function Tests; Naphthoquinones; Prothrombin; Retinoids; Vitamin K

Topics: Antifibrinolytic Agents; Hepatitis; Hepatitis A; Humans; Jaundice; Jaundice, Obstructive; Vitamin K

Topics: Antifibrinolytic Agents; Heparin Antagonists; Hepatitis; Humans; Jaundice; Vitamin K

Topics: Antifibrinolytic Agents; Hemostatics; Humans; Jaundice; Prothrombin; Vitamin K

Topics: Antifibrinolytic Agents; Bilirubin; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice; Vitamin K

Topics: Humans; Jaundice; Vitamin A; Vitamin K; Vitamins