vitamin-k-semiquinone-radical has been researched along with Hemochromatosis* in 2 studies
2 other study(ies) available for vitamin-k-semiquinone-radical and Hemochromatosis
Article | Year |
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Labial salivary gland biopsy in the investigation of neonatal hemochromatosis.
Topics: Biopsy; Carnitine; Cholagogues and Choleretics; Female; Hemochromatosis; Humans; Immunoglobulins, Intravenous; Infant, Newborn; Infant, Premature; Iron; Lip; Liver Failure; Liver Regeneration; Mouth Mucosa; Salivary Glands, Minor; Ursodeoxycholic Acid; Vitamin K; Vitamins | 2011 |
Successful pregnancy outcome following maternal intravenous immunoglobulin treatment in a woman with recurrent perinatal haemochromatosis.
We report a case of successful pregnancy outcome following maternal intravenous immunoglobulin treatment in a woman with previous history of recurrent fetal hydrops secondary to perinatal haemochromatosis.. A 32-year old woman had two successive pregnancies complicated by fetal hydrops and perinatal deaths. Pathological examination of the fetus showed severe liver destruction with siderosis of hepatocytes at extrahepatic sites, but sparing of the reticulo-endothelial elements, consistent with the diagnosis of perinatal haemochromatosis. In the subsequent pregnancy, maternal intravenous immunoglobulin was administered weekly from the 18th week of gestation until delivery by elective caesarean section at 38 weeks. The infant was treated with desferrioxamine, N-acetylcysteine, vitamins K and E.. The infant was born in good health, but had high serum ferritin levels, markedly elevated percent transferrin saturation, and mild transient derangement of liver and coagulation function. The infant made an excellent recovery and the treatment was stopped at 7 weeks of age. The liver and coagulation parameters and the serum ferritin levels returned to normal values.. Haemochromatosis should be considered in the differential diagnosis of hydrops fetalis. The recurrence risk is high, and immunomodulation with intravenous immunoglobulin treatment appears to alter the course of the disease with better infant survival. Topics: Acetylcysteine; Adult; Deferoxamine; Diagnosis, Differential; Female; Ferritins; Fetal Diseases; Free Radical Scavengers; Gestational Age; Hemochromatosis; Humans; Hydrops Fetalis; Infant, Newborn; Live Birth; Liver Failure, Acute; Pregnancy; Recurrence; Treatment Outcome; Vitamin E; Vitamin K | 2006 |