vitamin-k-semiquinone-radical and Hematologic-Diseases

To assess the quality of long-term anticoagulation therapy with antivitamin-K in patients with atrial fibrillation by measuring the TTR and to determine the factors associated with a good TTR.. This is an observational study conducted over a period of three years (from January 2013 until December 2015) in the outpatient clinic of cardiology of Farhat Hached hospital of Sousse, Tunisia. Pre-established individual plugs were used for data collection. The data analysis was performed using the SPSS Software, version 20.. Overall, 200 patients were eligible. Half of the patients did not know the risks of AVK and 29.1% were unaware of their interest. The average TTR was 57.3±18.2%. Good control of anticoagulation was obtained in 24.5% of patients. Those with a≥70% were more autonomous, observant, of urban origin, living in Sousse and Kairouan, with good knowledge about AVK and having a small left atrium. The factors associated negatively with TTR were hypertension, diabetes, old AF, hematological diseases, high number of medications taken daily and the presence of mitral insufficiency, mitral valve replacement, a tricuspid insufficiency or a tricuspid plasty.. The quality of AVK anticoagulation in AF patients is insufficient. Improving this indicator would reduce the morbidity and mortality associated with AVK treatment.

Topics: Adult; Aged; Ambulatory Care; Anticoagulants; Atrial Fibrillation; Diabetic Angiopathies; Female; Health Knowledge, Attitudes, Practice; Heart Valve Diseases; Hematologic Diseases; Hemorrhage; Humans; Hypertension; International Normalized Ratio; Male; Middle Aged; Polypharmacy; Quality of Health Care; Risk Factors; Thromboembolism; Thrombolytic Therapy; Tunisia; Vitamin K

Topics: Animals; Dog Diseases; Dogs; Female; Hematologic Diseases; Vitamin K; Warfarin

Topics: Adolescent; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antibiotics, Antitubercular; Benzene; Blood Transfusion; Cortisone; Folic Acid; Hematologic Diseases; Hematology; Iron; Occupational Diseases; Toxicology; Vitamin B 12; Vitamin K

Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Benzene; Cortisone; Female; Folic Acid; Hematologic Diseases; Occupational Diseases; Pregnancy; Pregnancy Complications; Prognosis; Toxicology; Vitamin K; Vitamins

Topics: Avitaminosis; Hematologic Diseases; Humans; Vitamin A; Vitamin K; Vitamins

Topics: Antifibrinolytic Agents; Erythroblastosis, Fetal; Female; Hematologic Diseases; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Vitamin K

Topics: Anemia; Anemia, Hemolytic; Child; Diagnosis, Differential; Erythroblastosis, Fetal; Hematologic Diseases; Infant; Virus Diseases; Vitamin K

Topics: Erythroblastosis, Fetal; Factor X; Fetal Blood; Hematologic Diseases; Hemorrhagic Disorders; Humans; Infant, Newborn; Vitamin K; Vitamin K Deficiency Bleeding

Topics: Erythroblastosis, Fetal; Hematologic Diseases; Humans; Infant, Newborn; Vitamin K