vitamin-k-semiquinone-radical and Fetal-Membranes--Premature-Rupture

Optimum perinatal outcome is only achieved by the prevention of premature birth. When preterm delivery is unavoidable, antenatal pharmacologic therapy will result in a reduction in the leading causes of neonatal morbidity and mortality, mainly respiratory distress syndrome (RDS), BPD, intraventricular haemorrhage (IVH) and sepsis. These treatments combined with meticulous intrapartum management will result in significant improvements in the neonatal and long-term outcome in the premature baby.

Topics: Chorioamnionitis; Female; Fetal Membranes, Premature Rupture; Genital Diseases, Female; Humans; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Obstetric Labor, Premature; Phenobarbital; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Care; Risk Factors; Vitamin K

A case of severe neonatal sepsis due to intrauterine infection with Capnocytophaga ochracea, complicated by hypotension, renal failure and disseminated intravascular coagulation, is reported. The role of Capnocytophaga as an organism of increasing importance in intrauterine and peripartum infections is discussed.

Topics: Ampicillin; Bacteremia; Capnocytophaga; Chorioamnionitis; Dopamine; Female; Fetal Membranes, Premature Rupture; Gram-Negative Bacterial Infections; Humans; Infant, Newborn; Infant, Premature; Pregnancy; Pregnancy Complications, Infectious; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Tobramycin; Vitamin K