vitamin k 3 has been researched along with Melanoma in 4 studies
Vitamin K 3: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacological concentration of arsenic in combination with a widely known oxidant, menadione was explored in this study to synergistically sensitize malignant melanoma cells to apoptosis." | 7.75 | Arsenic induced apoptosis in malignant melanoma cells is enhanced by menadione through ROS generation, p38 signaling and p53 activation. ( Chaudhuri, K; Chowdhury, R; Chowdhury, S; Mandal, C; Roychoudhury, P, 2009) |
| " Pharmacological concentration of arsenic in combination with a widely known oxidant, menadione was explored in this study to synergistically sensitize malignant melanoma cells to apoptosis." | 3.75 | Arsenic induced apoptosis in malignant melanoma cells is enhanced by menadione through ROS generation, p38 signaling and p53 activation. ( Chaudhuri, K; Chowdhury, R; Chowdhury, S; Mandal, C; Roychoudhury, P, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lakhter, AJ | 1 |
| Hamilton, J | 1 |
| Dagher, PC | 1 |
| Mukkamala, S | 1 |
| Hato, T | 1 |
| Dong, XC | 1 |
| Mayo, LD | 1 |
| Harris, RA | 1 |
| Shekhar, A | 1 |
| Ivan, M | 1 |
| Brustovetsky, N | 1 |
| Naidu, SR | 1 |
| Tremante, E | 1 |
| Santarelli, L | 1 |
| Lo Monaco, E | 1 |
| Sampaoli, C | 1 |
| Ingegnere, T | 1 |
| Guerrieri, R | 1 |
| Tomasetti, M | 1 |
| Giacomini, P | 1 |
| Chowdhury, R | 1 |
| Chowdhury, S | 1 |
| Roychoudhury, P | 1 |
| Mandal, C | 1 |
| Chaudhuri, K | 1 |
| Shah, M | 1 |
| Stebbins, JL | 1 |
| Dewing, A | 1 |
| Qi, J | 1 |
| Pellecchia, M | 1 |
| Ronai, ZA | 1 |
4 other studies available for vitamin k 3 and Melanoma
| Article | Year |
|---|---|
Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma.
Topics: Animals; Carrier Proteins; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Glycolysi | 2014 |
Sub-apoptotic dosages of pro-oxidant vitamin cocktails sensitize human melanoma cells to NK cell lysis.
Topics: alpha-Tocopherol; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascorbic Acid; Cell Lin | 2015 |
Arsenic induced apoptosis in malignant melanoma cells is enhanced by menadione through ROS generation, p38 signaling and p53 activation.
Topics: Animals; Antifibrinolytic Agents; Apoptosis; Arsenic; Arsenites; Gene Expression Regulation, Enzymol | 2009 |
Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis.
Topics: Animals; Biological Assay; Cell Line; Enzyme Inhibitors; Humans; Hypoxia; Hypoxia-Inducible Factor 1 | 2009 |