vitamin k 3 has been researched along with Leukemia in 9 studies
Vitamin K 3: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leukemia lymphocytes were more sensitive to combined administration of anticancer drug (everolimus or barasertib) plus vitamins C and K3, compared to normal lymphocytes." | 7.88 | Vitamins C and K3: A Powerful Redox System for Sensitizing Leukemia Lymphocytes to Everolimus and Barasertib. ( Aoki, I; Bakalova, R; Getsov, P; Ivanova, D; Lazarova, D; Zhelev, Z, 2018) |
| "The flavonoid quercetin and menadione (vitamin K3) are known as potent apoptogens in human leukemia Jurkat T cells." | 7.80 | Novel insights into the antiproliferative effects and synergism of quercetin and menadione in human leukemia Jurkat T cells. ( Babes, R; Baran, I; Dimancea, A; Filippi, A; Ganea, C; Goicea, A; Iftime, A; Ionescu, D; Irimia, R; Mocanu, MM; Neagu, A; Popescu, V; Tofolean, IT, 2014) |
| "Leukemia lymphocytes were more sensitive to combined administration of anticancer drug (everolimus or barasertib) plus vitamins C and K3, compared to normal lymphocytes." | 3.88 | Vitamins C and K3: A Powerful Redox System for Sensitizing Leukemia Lymphocytes to Everolimus and Barasertib. ( Aoki, I; Bakalova, R; Getsov, P; Ivanova, D; Lazarova, D; Zhelev, Z, 2018) |
| "The flavonoid quercetin and menadione (vitamin K3) are known as potent apoptogens in human leukemia Jurkat T cells." | 3.80 | Novel insights into the antiproliferative effects and synergism of quercetin and menadione in human leukemia Jurkat T cells. ( Babes, R; Baran, I; Dimancea, A; Filippi, A; Ganea, C; Goicea, A; Iftime, A; Ionescu, D; Irimia, R; Mocanu, MM; Neagu, A; Popescu, V; Tofolean, IT, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Asami, S | 1 |
| Suzuki, M | 1 |
| Nakayama, T | 1 |
| Shimoda, Y | 1 |
| Miura, M | 1 |
| Kato, K | 1 |
| Tokuda, E | 1 |
| Ono, S | 1 |
| Kawakubo, T | 1 |
| Nishizawa, K | 1 |
| Yamanaka, K | 1 |
| Suzuki, T | 1 |
| Ivanova, D | 1 |
| Zhelev, Z | 1 |
| Lazarova, D | 1 |
| Getsov, P | 1 |
| Bakalova, R | 1 |
| Aoki, I | 1 |
| Ibrahim, M | 1 |
| Mendis, N | 1 |
| Roma, A | 1 |
| Jayanth, P | 1 |
| Minden, MD | 1 |
| Spagnuolo, PA | 1 |
| Baran, I | 3 |
| Ionescu, D | 1 |
| Filippi, A | 1 |
| Mocanu, MM | 3 |
| Iftime, A | 1 |
| Babes, R | 1 |
| Tofolean, IT | 1 |
| Irimia, R | 1 |
| Goicea, A | 1 |
| Popescu, V | 1 |
| Dimancea, A | 1 |
| Neagu, A | 1 |
| Ganea, C | 3 |
| Scordino, A | 2 |
| Musumeci, F | 2 |
| Barresi, V | 2 |
| Tudisco, S | 1 |
| Privitera, S | 2 |
| Grasso, R | 2 |
| Condorelli, DF | 2 |
| Ursu, I | 2 |
| Baran, V | 1 |
| Katona, E | 1 |
| Gulino, M | 2 |
| Ungureanu, R | 1 |
| Surcel, M | 1 |
| Ursaciuc, C | 1 |
| Yeo, HS | 1 |
| Shehzad, A | 1 |
| Lee, YS | 1 |
| Garaiman, A | 1 |
| Musso, N | 1 |
| Cirrone, GA | 1 |
| Cuttone, G | 1 |
| Verrax, J | 1 |
| Delvaux, M | 1 |
| Beghein, N | 1 |
| Taper, H | 1 |
| Gallez, B | 1 |
| Buc Calderon, P | 1 |
| Hill, JW | 1 |
| Evans, MK | 1 |
9 other studies available for vitamin k 3 and Leukemia
| Article | Year |
|---|---|
Apoptotic Effects of a Thioether Analog of Vitamin K
Topics: Antineoplastic Agents; Apoptosis; Humans; Jurkat Cells; Leukemia; Phosphorylation; Vitamin K 3 | 2021 |
Vitamins C and K3: A Powerful Redox System for Sensitizing Leukemia Lymphocytes to Everolimus and Barasertib.
Topics: Antineoplastic Agents; Apoptosis; Ascorbic Acid; Cell Survival; Cells, Cultured; Everolimus; Humans; | 2018 |
Anti-leukemia effect of vitamin K3 is mediated through mitochondrial complexes I and II.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Electron T | 2019 |
Novel insights into the antiproliferative effects and synergism of quercetin and menadione in human leukemia Jurkat T cells.
Topics: Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Humans; Jurkat | 2014 |
Effects of menadione, hydrogen peroxide, and quercetin on apoptosis and delayed luminescence of human leukemia Jurkat T-cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Flow Cytometry; Humans; Hydrogen Peroxide; Ju | 2010 |
Prostaglandin E2 blocks menadione-induced apoptosis through the Ras/Raf/Erk signaling pathway in promonocytic leukemia cell lines.
Topics: Apoptosis; Cell Survival; Cell Transformation, Neoplastic; Cyclic AMP-Dependent Protein Kinases; Din | 2012 |
Detailed analysis of apoptosis and delayed luminescence of human leukemia Jurkat T cells after proton irradiation and treatments with oxidant agents and flavonoids.
Topics: Apoptosis; Catechin; Cell Cycle; Cell Survival; Clone Cells; Flavonoids; Humans; Hydrogen Peroxide; | 2012 |
Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study.
Topics: Adenosine Triphosphate; Apoptosis; Ascorbic Acid; Caspase 3; Caspases; Cell Line, Tumor; Free Radica | 2005 |
A novel R229Q OGG1 polymorphism results in a thermolabile enzyme that sensitizes KG-1 leukemia cells to DNA damaging agents.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alleles; Amino Acid Substitution; Antineoplastic Agents; Cell Line, Tum | 2007 |