vitamin k 3 has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 5 studies
Vitamin K 3: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, CS | 1 |
| Lewis, AH | 1 |
| Chen, TJ | 1 |
| Bridges, CS | 1 |
| Shen, Y | 1 |
| Suppipat, K | 1 |
| Puppi, M | 1 |
| Tomolonis, JA | 1 |
| Pang, PD | 1 |
| Mistretta, TA | 1 |
| Ma, L | 1 |
| Green, MR | 1 |
| Rau, R | 1 |
| Lacorazza, HD | 1 |
| Xiao, FY | 1 |
| Zhou, FJ | 1 |
| Yuan, F | 1 |
| Kuang, W | 1 |
| Zhou, G | 1 |
| Zhou, HH | 1 |
| Cao, S | 1 |
| Huang, J | 1 |
| Lu, Z | 1 |
| Xiao, Y | 1 |
| He, B | 1 |
| Pan, C | 1 |
| Zhou, X | 1 |
| Xu, N | 1 |
| Liu, X | 1 |
| Verrax, J | 2 |
| Stockis, J | 2 |
| Tison, A | 1 |
| Taper, HS | 1 |
| Calderon, PB | 2 |
| Vanbever, S | 1 |
| Taper, H | 1 |
5 other studies available for vitamin k 3 and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
| Article | Year |
|---|---|
A KLF4-DYRK2-mediated pathway regulating self-renewal in CML stem cells.
Topics: Animals; Cell Survival; Dyrk Kinases; Fusion Proteins, bcr-abl; Gene Deletion; Humans; Kruppel-Like | 2019 |
The potentiation of menadione on imatinib by downregulation of ABCB1 expression.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; Cell | 2020 |
Inhibition of Siah2 Ubiquitin Ligase by Vitamin K3 Attenuates Chronic Myeloid Leukemia Chemo-Resistance in Hypoxic Microenvironment.
Topics: Adult; Apoptosis; Cell Cycle Checkpoints; Cell Hypoxia; Drug Resistance, Neoplasm; Female; Gene Expr | 2018 |
Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice.
Topics: Animals; Ascorbic Acid; Cell Death; Cell Line, Tumor; Disease Models, Animal; Humans; K562 Cells; Le | 2006 |
Role of glycolysis inhibition and poly(ADP-ribose) polymerase activation in necrotic-like cell death caused by ascorbate/menadione-induced oxidative stress in K562 human chronic myelogenous leukemic cells.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Enzyme Activation; Glycolysis; Humans; Leukemia, Myelogenous | 2007 |