vitamin k 3 has been researched along with Insulinoma in 4 studies
Vitamin K 3: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Menadione, which produces H(2)O(2) via redox cycling mechanism in a dose-dependent manner, was investigated for its effect on β-cell metabolism and insulin secretion in INS-1 832/13, a rat β-cell insulinoma cell line, and primary rodent islets." | 3.78 | The level of menadione redox-cycling in pancreatic β-cells is proportional to the glucose concentration: role of NADH and consequences for insulin secretion. ( Gray, JP; Heart, E; Palo, M; Smith, PJ; Womack, T, 2012) |
| " Mitochondrial catalase overexpression also preferentially protected against the toxicity of interleukin-1beta (IL-1beta) and a proinflammatory cytokine mixture (IL-1beta, tumor necrosis factor-alpha [TNF-alpha], and gamma-interferon [IFN-gamma]) that is more toxic than IL-1beta alone." | 1.32 | Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines. ( Gurgul, E; Jörns, A; Lenzen, S; Lortz, S; Tiedge, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heart, E | 1 |
| Palo, M | 1 |
| Womack, T | 1 |
| Smith, PJ | 1 |
| Gray, JP | 1 |
| Park, SY | 1 |
| Chang, I | 1 |
| Kim, JY | 1 |
| Kang, SW | 1 |
| Park, SH | 1 |
| Singh, K | 1 |
| Lee, MS | 1 |
| Gurgul, E | 1 |
| Lortz, S | 1 |
| Tiedge, M | 1 |
| Jörns, A | 1 |
| Lenzen, S | 1 |
| LeDoux, SP | 1 |
| Wilson, GL | 1 |
1 review available for vitamin k 3 and Insulinoma
| Article | Year |
|---|---|
Base excision repair of mitochondrial DNA damage in mammalian cells.
Topics: Alkylation; Animals; Bleomycin; Caspases; Cerebellar Cortex; CHO Cells; Cricetinae; Cricetulus; DNA | 2001 |
3 other studies available for vitamin k 3 and Insulinoma
| Article | Year |
|---|---|
The level of menadione redox-cycling in pancreatic β-cells is proportional to the glucose concentration: role of NADH and consequences for insulin secretion.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Glucose; Hydrogen Peroxide; Insulin; In | 2012 |
Resistance of mitochondrial DNA-depleted cells against cell death: role of mitochondrial superoxide dismutase.
Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; DNA, Mitochondrial; Doxorubicin; D | 2004 |
Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines.
Topics: Animals; Antifibrinolytic Agents; Antineoplastic Agents; Catalase; Cell Line, Tumor; Cytokines; Gene | 2004 |