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vitamin k 3 and Disease Models, Animal

vitamin k 3 has been researched along with Disease Models, Animal in 22 studies

Vitamin K 3: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Epilepsy is a debilitating disease affecting 1-2% of the world's population."1.40Novel Vitamin K analogs suppress seizures in zebrafish and mouse models of epilepsy. ( Bestman, JE; Chan, SS; Chou, CJ; Inks, ES; Josey, BJ; Rahn, JJ; Rogers, CE; Stackley, KD, 2014)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (45.45)29.6817
2010's10 (45.45)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Kumar, S1
Malachowski, WP1
DuHadaway, JB1
LaLonde, JM1
Carroll, PJ1
Jaller, D1
Metz, R1
Prendergast, GC1
Muller, AJ1
Lai, TS1
Liu, Y1
Tucker, T1
Daniel, KR1
Sane, DC1
Toone, E1
Burke, JR1
Strittmatter, WJ1
Greenberg, CS1
O'Donnell, G1
Poeschl, R1
Zimhony, O1
Gunaratnam, M1
Moreira, JB1
Neidle, S1
Evangelopoulos, D1
Bhakta, S1
Malkinson, JP1
Boshoff, HI1
Lenaerts, A1
Gibbons, S1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Ibitoye, OB1
Ajiboye, TO1
Oliveira, LB1
Celes, FS1
Paiva, CN1
de Oliveira, CI1
Tietz Bogert, PS1
Huang, BQ1
Gradilone, SA2
Masyuk, TV2
Moulder, GL1
Ekker, SC1
Larusso, NF2
Rahn, JJ1
Bestman, JE1
Josey, BJ1
Inks, ES1
Stackley, KD1
Rogers, CE1
Chou, CJ1
Chan, SS1
Dean, MA1
Olsen, RJ1
Long, SW1
Rosato, AE1
Musser, JM1
Jan, YH1
Richardson, JR1
Baker, AA1
Mishin, V1
Heck, DE1
Laskin, DL1
Laskin, JD1
Schamberger, AC1
Schiller, HB1
Fernandez, IE1
Sterclova, M1
Heinzelmann, K1
Hennen, E1
Hatz, R1
Behr, J1
Vašáková, M1
Mann, M1
Eickelberg, O1
Staab-Weijnitz, CA1
Rush, JS1
Bingaman, DP1
Chaney, PG1
Wax, MB1
Ceresa, BP1
Hong, JY1
Lebofsky, M1
Farhood, A1
Jaeschke, H1
Radtke, BN1
Stroope, AJ1
Banales, JM1
Masyuk, AI1
Gajdos, GB1
Chandok, N1
Bakeberg, JL1
Ward, CJ1
Ritman, EL1
Kiyokawa, H1
Vepsäläinen, S1
Koivisto, H1
Pekkarinen, E1
Mäkinen, P1
Dobson, G1
McDougall, GJ1
Stewart, D1
Haapasalo, A1
Karjalainen, RO1
Tanila, H1
Hiltunen, M1
Chaves, GM1
da Silva, WP1
Hwang, CS1
Rhie, GE1
Oh, JH1
Huh, WK1
Yim, HS1
Kang, SO1
Narasipura, SD1
Ault, JG1
Behr, MJ1
Chaturvedi, V1
Chaturvedi, S1
Bates, DM1
von Eiff, C1
McNamara, PJ1
Peters, G1
Yeaman, MR1
Bayer, AS1
Proctor, RA1
Tariq, M1
Al Moutaery, A1
Verrax, J1
Stockis, J1
Tison, A1
Taper, HS1
Calderon, PB1
Nichols, KD1
Kirby, GM1

Other Studies

22 other studies available for vitamin k 3 and Disease Models, Animal

ArticleYear
Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cell Survival; Computer Simulatio

2008
Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries.
    Chemistry & biology, 2008, Sep-22, Volume: 15, Issue:9

    Topics: Animals; Calcium; Combinatorial Chemistry Techniques; Disease Models, Animal; Drosophila melanogaste

2008
Bioactive pyridine-N-oxide disulfides from Allium stipitatum.
    Journal of natural products, 2009, Mar-27, Volume: 72, Issue:3

    Topics: 2,2'-Dipyridyl; Alkaloids; Allium; Animals; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic

2009
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Protocatechuic acid protects against menadione-induced liver damage by up-regulating nuclear erythroid-related factor 2.
    Drug and chemical toxicology, 2020, Volume: 43, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Mo

2020
The Paradoxical Leishmanicidal Effects of Superoxide Dismutase (SOD)-Mimetic Tempol in
    Frontiers in cellular and infection microbiology, 2019, Volume: 9

    Topics: Acetophenones; Animals; Antioxidants; Cyclic N-Oxides; Disease Models, Animal; Ditiocarb; Drug Thera

2019
The zebrafish as a model to study polycystic liver disease.
    Zebrafish, 2013, Volume: 10, Issue:2

    Topics: Animals; Antineoplastic Agents; Calcium-Binding Proteins; Cysts; Disease Models, Animal; DNA Helicas

2013
Novel Vitamin K analogs suppress seizures in zebrafish and mouse models of epilepsy.
    Neuroscience, 2014, Feb-14, Volume: 259

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Cell Line; Disease Models, Animal; Dose-Response R

2014
Identification of point mutations in clinical Staphylococcus aureus strains that produce small-colony variants auxotrophic for menadione.
    Infection and immunity, 2014, Volume: 82, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Genome, Bacterial; Gentamicins; Mice; Microb

2014
Vitamin K3 (menadione) redox cycling inhibits cytochrome P450-mediated metabolism and inhibits parathion intoxication.
    Toxicology and applied pharmacology, 2015, Oct-01, Volume: 288, Issue:1

    Topics: Acetylcholinesterase; Activation, Metabolic; Animals; Cholinesterase Inhibitors; Cytochrome P-450 En

2015
Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease.
    Scientific reports, 2016, 07-20, Volume: 6

    Topics: Aged; Animals; Antioxidants; Bleomycin; Bronchi; Bronchoalveolar Lavage Fluid; Demography; Disease M

2016
Administration of Menadione, Vitamin K3, Ameliorates Off-Target Effects on Corneal Epithelial Wound Healing Due to Receptor Tyrosine Kinase Inhibition.
    Investigative ophthalmology & visual science, 2016, Nov-01, Volume: 57, Issue:14

    Topics: Animals; Cell Line; Disease Models, Animal; Epidermal Growth Factor; Epithelium, Corneal; ErbB Recep

2016
Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:3

    Topics: Alanine Transaminase; Aldehydes; Animals; Antifibrinolytic Agents; Apoptosis; Caspases; Chemical and

2009
Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease.
    Gastroenterology, 2012, Volume: 142, Issue:3

    Topics: Animals; Bile Ducts, Intrahepatic; cdc25 Phosphatases; Cell Cycle; Cell Proliferation; Cells, Cultur

2012
Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; An

2013
Superoxide dismutases and glutaredoxins have a distinct role in the response of Candida albicans to oxidative stress generated by the chemical compounds menadione and diamide.
    Memorias do Instituto Oswaldo Cruz, 2012, Volume: 107, Issue:8

    Topics: Animals; Candida albicans; Candidiasis; Diamide; Disease Models, Animal; Drug Resistance, Fungal; Fe

2012
Copper- and zinc-containing superoxide dismutase (Cu/ZnSOD) is required for the protection of Candida albicans against oxidative stresses and the expression of its full virulence.
    Microbiology (Reading, England), 2002, Volume: 148, Issue:Pt 11

    Topics: Adaptation, Biological; Animals; Candida albicans; Candidiasis; Disease Models, Animal; Humans; Lysi

2002
Characterization of Cu,Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: role in biology and virulence.
    Molecular microbiology, 2003, Volume: 47, Issue:6

    Topics: Animals; Brain; Cryptococcus neoformans; Disease Models, Animal; Fungal Proteins; Genetic Complement

2003
Staphylococcus aureus menD and hemB mutants are as infective as the parent strains, but the menadione biosynthetic mutant persists within the kidney.
    The Journal of infectious diseases, 2003, May-15, Volume: 187, Issue:10

    Topics: Animals; Blood Proteins; Disease Models, Animal; Drug Resistance, Bacterial; Endocarditis, Bacterial

2003
Menadione protects gastric mucosa against ethanol-induced ulcers.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2005, Volume: 56, Issue:6

    Topics: Administration, Oral; Animals; Antifibrinolytic Agents; Disease Models, Animal; Dose-Response Relati

2005
Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice.
    Biochemical pharmacology, 2006, Sep-14, Volume: 72, Issue:6

    Topics: Animals; Ascorbic Acid; Cell Death; Cell Line, Tumor; Disease Models, Animal; Humans; K562 Cells; Le

2006
Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress.
    Biochemical pharmacology, 2008, Mar-01, Volume: 75, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Catalase; Cytochr

2008