vitamin k 3 has been researched along with Chemical and Drug Induced Liver Injury in 7 studies
Vitamin K 3: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Ibitoye, OB | 1 |
| Ajiboye, TO | 1 |
| Hong, JY | 1 |
| Lebofsky, M | 1 |
| Farhood, A | 1 |
| Jaeschke, H | 1 |
| Ip, SP | 1 |
| Woo, KY | 1 |
| Lau, OW | 1 |
| Che, CT | 1 |
| Chiu, PY | 1 |
| Leung, HY | 1 |
| Poon, MK | 1 |
| Mak, DH | 1 |
| Ko, KM | 1 |
7 other studies available for vitamin k 3 and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Protocatechuic acid protects against menadione-induced liver damage by up-regulating nuclear erythroid-related factor 2.
Topics: Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Mo | 2020 |
Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation.
Topics: Alanine Transaminase; Aldehydes; Animals; Antifibrinolytic Agents; Apoptosis; Caspases; Chemical and | 2009 |
Hepatoprotective effect of Sabina przewalskii against menadione-induced toxicity.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, D | 2004 |
Effects of schisandrin B enantiomers on cellular glutathione and menadione toxicity in AML12 hepatocytes.
Topics: Animals; Cell Line; Chemical and Drug Induced Liver Injury; Cyclooctanes; Glutamate-Cysteine Ligase; | 2006 |