vitamin k 3 has been researched along with Breast Neoplasms in 14 studies
Vitamin K 3: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Calcitriol or 1,25(OH)(2)D(3) is a negative growth regulator of MCF-7 breast cancer cells." | 3.75 | Antiproliferative action of menadione and 1,25(OH)2D3 on breast cancer cells. ( Marchionatti, AM; Narvaez, CJ; Picotto, G; Tolosa de Talamoni, NG; Welsh, J, 2009) |
| "Early stage primary breast cancers selected a priori for lower ER content (21-87 fmol/mg; n=59) and known clinical outcome showed two- to four-fold increased p50 and p65 NFkappaB DNA-binding over a second set of primary breast cancers with higher ER content (>100 fmol/mg; n=22)." | 1.33 | Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers. ( Benz, CC; Eppenberger, U; Eppenberger-Castori, S; Marx, C; Scott, GK; Yau, C; Zhou, Y, 2005) |
| " With the exception of 5-O-PN, all the other naringenins showed only weak toxic effects at concentrations below 50 micromol/l." | 1.32 | Toxicity and cell cycle effects of synthetic 8-prenylnaringenin and derivatives in human cells. ( Gutzeit, HO; Henker, Y; Metz, P; Schwab, P; Tokalov, SV, 2004) |
| "Global gene expression patterns in breast cancer cells after treatment with oxidants (hydrogen peroxide, menadione, and t-butyl hydroperoxide) were investigated in three replicate experiments." | 1.31 | Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells. ( Chandramouli, VR; Chen, Y; Chuang, YY; Coffin, D; Cook, JA; DeGraff, W; Liu, ET; Mitchell, JB; Russo, A; Tsai, MH; Yan, H; Zhao, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (71.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Guizzardi, S | 1 |
| Picotto, G | 2 |
| Rodriguez, V | 1 |
| Welsh, J | 2 |
| Narvaez, C | 1 |
| Bohl, L | 1 |
| Tolosa de Talamoni, N | 1 |
| Yang, GG | 1 |
| Zhang, H | 1 |
| Zhang, DY | 1 |
| Cao, Q | 1 |
| Yang, J | 1 |
| Ji, LN | 1 |
| Mao, ZW | 1 |
| Sajadimajd, S | 1 |
| Yazdanparast, R | 1 |
| Kumar, B | 1 |
| Kumar, A | 1 |
| Pandey, BN | 1 |
| Mishra, KP | 1 |
| Hazra, B | 1 |
| Marchionatti, AM | 1 |
| Narvaez, CJ | 1 |
| Tolosa de Talamoni, NG | 1 |
| Akiyoshi, T | 1 |
| Matzno, S | 1 |
| Sakai, M | 1 |
| Okamura, N | 1 |
| Matsuyama, K | 1 |
| Ryu, CS | 1 |
| Kwak, HC | 1 |
| Lee, KS | 1 |
| Kang, KW | 1 |
| Oh, SJ | 1 |
| Lee, KH | 1 |
| Kim, HM | 1 |
| Ma, JY | 1 |
| Kim, SK | 1 |
| Chuang, YY | 1 |
| Chen, Y | 1 |
| Chandramouli, VR | 1 |
| Cook, JA | 1 |
| Coffin, D | 1 |
| Tsai, MH | 1 |
| DeGraff, W | 1 |
| Yan, H | 1 |
| Zhao, S | 1 |
| Russo, A | 1 |
| Liu, ET | 1 |
| Mitchell, JB | 1 |
| Burdette, JE | 1 |
| Chen, SN | 1 |
| Lu, ZZ | 1 |
| Xu, H | 1 |
| White, BE | 1 |
| Fabricant, DS | 1 |
| Liu, J | 1 |
| Fong, HH | 1 |
| Farnsworth, NR | 1 |
| Constantinou, AI | 1 |
| Van Breemen, RB | 1 |
| Pezzuto, JM | 1 |
| Bolton, JL | 1 |
| Düssmann, H | 1 |
| Kögel, D | 1 |
| Rehm, M | 1 |
| Prehn, JH | 1 |
| Tokalov, SV | 1 |
| Henker, Y | 1 |
| Schwab, P | 1 |
| Metz, P | 1 |
| Gutzeit, HO | 1 |
| Jung, J | 1 |
| Ishida, K | 1 |
| Nishihara, T | 1 |
| Zhou, Y | 1 |
| Eppenberger-Castori, S | 1 |
| Marx, C | 1 |
| Yau, C | 1 |
| Scott, GK | 2 |
| Eppenberger, U | 1 |
| Benz, CC | 2 |
| Atsriku, C | 1 |
| Kaminker, P | 1 |
| Held, J | 1 |
| Gibson, B | 1 |
| Baldwin, MA | 1 |
14 other studies available for vitamin k 3 and Breast Neoplasms
| Article | Year |
|---|---|
Combined treatment of menadione and calcitriol increases the antiproliferative effect by promoting oxidative/nitrosative stress, mitochondrial dysfunction, and autophagy in breast cancer MCF-7 cells.
Topics: Antineoplastic Agents; Autophagy; Breast Neoplasms; Calcitriol; Cell Cycle; Cell Proliferation; Cell | 2020 |
Cancer-specific chemotherapeutic strategy based on the vitamin K3 mediated ROS regenerative feedback and visualized drug release in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Coordination Complexes; | 2018 |
Differential behaviors of trastuzumab-sensitive and -resistant SKBR3 cells treated with menadione reveal the involvement of Notch1/Akt/FOXO1 signaling elements.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Resistanc | 2015 |
Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells.
Topics: Acetylcysteine; Allopurinol; Animals; Antimycin A; Apoptosis; bcl-2-Associated X Protein; Breast Neo | 2009 |
Antiproliferative action of menadione and 1,25(OH)2D3 on breast cancer cells.
Topics: Animals; Antioxidants; Breast Neoplasms; Calcitriol; Cell Line, Tumor; Cell Shape; Dose-Response Rel | 2009 |
The potential of vitamin K3 as an anticancer agent against breast cancer that acts via the mitochondria-related apoptotic pathway.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 7; Caspase 9; Cell Line, Tumor; DNA Frag | 2009 |
Sulfur amino acid metabolism in doxorubicin-resistant breast cancer cells.
Topics: Amino Acids, Sulfur; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Mem | 2011 |
Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells.
Topics: Breast Neoplasms; Cluster Analysis; Gene Expression; Gene Expression Profiling; Gene Expression Regu | 2002 |
Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles.
Topics: Antioxidants; Biphenyl Compounds; Breast Neoplasms; Cimicifuga; DNA Damage; Estrogen Receptor alpha; | 2002 |
Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis.
Topics: Apoptosis; Breast Neoplasms; Cycloheximide; Female; Genes, Reporter; Green Fluorescent Proteins; Hum | 2003 |
Toxicity and cell cycle effects of synthetic 8-prenylnaringenin and derivatives in human cells.
Topics: Benzimidazoles; Breast Neoplasms; Carbocyanines; Cell Division; Cell Line, Tumor; Cell Membrane; Dos | 2004 |
Anti-estrogenic activity of fifty chemicals evaluated by in vitro assays.
Topics: Binding, Competitive; Breast Neoplasms; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Fe | 2004 |
Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Female; Hu | 2005 |
Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylation.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Histones; Humans; Keratin-8; Ke | 2005 |