vitamin-b-12 and Pyelonephritis

Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Coenzymes; Copper; Copper Sulfate; Drug Therapy, Combination; Female; Humans; Male; Pyelonephritis; Pyridoxal Phosphate; Vitamin B 12; Zinc

It is difficult to assess the vitamin B12 metabolism in chronic renal insufficiency. In varying numbers out of a total of 88 nephropathy patients with varying degrees of insufficiency (22 patients without restriction of kidney function, 53 patients with chronic renal insufficiency in the stage of compensated retention and 13 haemodialysis patients) the Schilling test was performed and the serum vitamin B12 level was measured in fasting and 4, 6, 8 and 10 hours after oral administration of 2000 micrograms of vitamin B12. Regardless of the volume of urine, the Schilling test must be treated critically with serum creatinine values between 150 and 300 mumol/l and beyond 300 mumol/l it is no longer of diagnostic value. Serum vitamin B12 measurement after oral administration of 2000 micrograms of vitamin B12 allows vitamin resorption in the ileum to be qualitatively demonstrated on the basis of the curve. In most renal insufficiency patients the serum vitamin B12 level was increased, but this does not exclude the possibility of vitamin B12 deficiency.

Topics: Adolescent; Adult; Aged; Cobalt Radioisotopes; Creatinine; Female; Glomerulonephritis; Humans; Intestinal Absorption; Kidney Failure, Chronic; Male; Middle Aged; Pyelonephritis; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency

Topics: Adrenal Gland Neoplasms; Adult; Binding Sites; Cells, Cultured; Centrifugation; Cobalt Radioisotopes; Dialysis; Female; Granulocytes; Hodgkin Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Lung Neoplasms; Male; Melanoma; Multiple Myeloma; Protein Binding; Proteinuria; Pyelonephritis; Time Factors; Vitamin B 12

Topics: Anemia, Aplastic; Anemia, Macrocytic; Blood Cell Count; Folic Acid; Folic Acid Deficiency; Humans; Iron; Middle Aged; Nalidixic Acid; Nutrition Disorders; Pyelonephritis; Sulfamethoxazole; Trimethoprim; Urea; Vitamin B 12; Vitamin B 12 Deficiency

Topics: Adult; Aged; Cobalt Isotopes; Diuresis; Diuretics; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Iodine Isotopes; Iodohippuric Acid; Kidney Function Tests; Male; Mannitol; Middle Aged; Pyelonephritis; Renal Artery Obstruction; Urea; Vasopressins; Vitamin B 12

Topics: Adolescent; Adult; Aged; Arteriosclerosis; Blood; Cholecystitis; Cobalt Isotopes; Colitis, Ulcerative; Creatine; Female; Glomerular Filtration Rate; Glomerulonephritis; Goiter; Humans; Hypertension; Inulin; Male; Middle Aged; Nephrocalcinosis; Pyelonephritis; Scleroderma, Systemic; Urine; Vitamin B 12

Topics: Acute Kidney Injury; Biological Assay; Blood Chemical Analysis; Glomerulonephritis; Kidney Diseases; Kidneys, Artificial; Mercury Poisoning; Nephritis; Nephritis, Interstitial; Postoperative Complications; Pyelonephritis; Renal Insufficiency; Solvents; Toxicology; Tuberculosis; Tuberculosis, Renal; Vitamin B 12; Wounds and Injuries

The serum vitamin B(12) level was abnormally high in 14 out of 32 cases of renal failure. This was probably due to impaired excretion of the vitamin, but the results of measurements of the rate of excretion of radioactive vitamin B(12) did not provide unequivocal evidence on this point; other possible explanations are discussed. Renal failure must be added to the causes of high serum B(12) levels.

Topics: Arteriosclerosis; Glomerulonephritis; Humans; Hypertension; Hypertension, Malignant; Kidney; Kidney Diseases; Nephritis; Nephrocalcinosis; Polycystic Kidney Diseases; Pyelonephritis; Renal Insufficiency; Vitamin B 12