vitamin-b-12 and Intestinal-Diseases--Parasitic

Topics: Absorption; Anemia; Diagnosis, Differential; Gastrectomy; Humans; Intestinal Diseases, Parasitic; Malabsorption Syndromes; Reference Values; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency

In summary, it appears that giardiasis, coccidiosis, cryptosporidiosis, strongyloidiasis, capillariasis and perhaps P. falciparum malaria are the only parasitic diseases which cause malabsorption of many nutrients. D. latum and A. lumbricoides interfere with vitamin B12 and vitamin A absorption, respectively. In view of the increasing use of immunosuppressive therapy, it is likely that malabsorption caused by intestinal parasites may become even more evident in the future.

Topics: Ancylostomiasis; Apicomplexa; Ascariasis; Capillaria; Coccidiosis; Diphyllobothriasis; Giardiasis; Humans; Intestinal Diseases, Parasitic; Malabsorption Syndromes; Malaria; Nematode Infections; Plasmodium falciparum; Protozoan Infections; Schistosomiasis; Strongyloidiasis; Vitamin A; Vitamin B 12

Topics: Adolescent; Anemia; Animals; Biological Transport; Blind Loop Syndrome; Calcium; Gastric Mucosa; Gastritis; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Ileum; Intestinal Absorption; Intestinal Diseases, Parasitic; Intestinal Mucosa; Intrinsic Factor; Male; Pancreatic Diseases; Radiation Effects; Rats; Thalassemia; Trypsin; Vitamin B 12; Vitamin B 12 Deficiency

Topics: Ascorbic Acid; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Developing Countries; Diet; Female; Gastrointestinal Diseases; Humans; Hygiene; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infections; Intestinal Diseases, Parasitic; Iron; Malabsorption Syndromes; Male; Nitrogen; Nutrition Disorders; Nutritional Requirements; Vitamin B 12

Topics: Bile; Biological Transport, Active; Enzymes; Folic Acid; Folic Acid Deficiency; Food Deprivation; Gastric Juice; Humans; Intestinal Absorption; Intestinal Diseases, Parasitic; Nutrition Disorders; Nutritional Requirements; Phenytoin; Polycythemia; Vitamin B 12; Vitamin B 12 Deficiency

Topics: Abetalipoproteinemia; Agammaglobulinemia; Animals; Bile Acids and Salts; Biological Transport; Biopsy; Carbohydrate Metabolism; Celiac Disease; Deficiency Diseases; Dermatitis Herpetiformis; Digestion; Endocrine System Diseases; Glutens; Glycoside Hydrolases; Histocytochemistry; Humans; Intestinal Absorption; Intestinal Diseases, Parasitic; Intestinal Mucosa; Intestine, Small; Intestines; Lymphatic Diseases; Malabsorption Syndromes; Methods; Monosaccharides; Protein-Losing Enteropathies; Psoriasis; Radiography; Sprue, Tropical; Vitamin B 12; Whipple Disease

A 61-year-old eutrophic male was diagnosed with vitamin B12 deficiency and megaloblastic anemia. A modified Schilling test suggested intestinal malabsorption unrelated to intrinsic factor deficiency. Subsequent colonoscopy revealed the presence of a Taenia tapeworm. The anemia resolved within days under therapy with niclosamide and temporary vitamin B12 supplements. The present case suggests that, in addition to other well-known parasitic agents, e.g., Diphyllobothrium latum and Giardia lamblia, Taenia infestation can also be a cause of intestinal vitamin B12 malabsorption.

Topics: Anemia, Megaloblastic; Animals; Anthelmintics; Food Parasitology; Humans; Intestinal Diseases, Parasitic; Malabsorption Syndromes; Male; Meat; Middle Aged; Niclosamide; Taeniasis; Vitamin B 12; Vitamin B 12 Deficiency

To determine prospectively plasma levels of vitamin B12 and folic acid in children with intestinal parasitic infection before and three months after antiparasitic treatment.. 3036 stool samples were collected from 1959 children and 939 cello-tape anal swabs were taken from 688 children for intestinal parasite investigation. Of these, 155 children were identified as having a parasitic infection; however, only 86 were followed up during this study: 26 children with Giardia lamblia infection were treated with tinidazole and metronidazole, pyrantel pamoate was used in the treatment of 40 children with Enterobius vermicularis, and 20 patients infected with Cryptosporidium parvum received only symptomatic treatment. Vitamin B12 and folic acid levels were measured by radioimmunoassay, before and three months after the completion of treatment.. Vitamin B12 serum concentrations did not show any significant differences among the three groups. There was a significant increase in vitamin B12 serum concentrations after three months of anti-parasitic treatment (630.57+/-200.97 vs. 667.97+/-181.55 pg/dL, p = 0.002, n = 86). Paired analysis in each group showed only significant increases for vitamin B12 in the Giardia lamblia group and in the Enterobius vermicularis group. No statistically significant differences were found for folic acid serum concentrations before and three months after treatment.. Patients with symptomatic infection by Giardia lamblia and Enterobius vermicularis have lower vitamin B12 levels than asymptomatic patients. This could reflect a more affected intestinal mucous. These results could present the opportunity to treat these parasitic infections and to use vitamin B12 supplementation in symptomatic children with Giardia lamblia and Enterobius vermicularis infection.

Topics: Adolescent; Child; Child, Preschool; Cryptosporidiosis; Drug Therapy; Enterobiasis; Feces; Female; Folic Acid; Giardiasis; Humans; Infant; Intestinal Diseases, Parasitic; Male; Spain; Vitamin B 12

The intestinal absorption of carbohydrate, fat, protein and vitamin B12, serum vitamin B12, serum and red cell folate levels were performed in 10 patients harbouring F. buski. No disturbance of carbohydrate, fat and protein absorption was observed but vitamin B12 absorption was found to be slightly lower than normal in 8 out of 10 patients, and serum vitamin B12 was also lower than normal in 4 out of 9 patients. Red cell and serum flolate levels were within the normal limits. Histological study of jejunal biopsy was normal in 7 out of 8 patients.

Topics: Adolescent; Adult; Child; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Erythrocytes; Fasciolidae; Female; Folic Acid; Humans; Infant, Newborn; Intestinal Absorption; Intestinal Diseases, Parasitic; Male; Middle Aged; Parasite Egg Count; Trematode Infections; Vitamin B 12

Topics: Adolescent; Anemia, Macrocytic; Anemia, Megaloblastic; Diphyllobothriasis; Feeding Behavior; Humans; Intestinal Diseases, Parasitic; Male; Niclosamide; Vitamin B 12

Topics: Adolescent; Adult; Female; Folic Acid; Giardiasis; Hemoglobins; Humans; Intestinal Absorption; Intestinal Diseases, Parasitic; Iron; Male; Metronidazole; Middle Aged; Vitamin B 12

Topics: Adolescent; Adult; Child; Female; Helminthiasis; Humans; Intestinal Diseases, Parasitic; Male; Sanitation; Socioeconomic Factors; Thailand; Trematode Infections; Vitamin B 12

Idiopathic enteropathy in the rural population of Iran was investigated through evaluation of 100 randomly selected apparently normal subjects. The evaluation included quantitation of the nutrient loss, presence of malabsorption, and small intestinal morphological abnormalities. The results show that: 1) there was no significant loss of major nutrients, 2) severe malabsorption was not present, 3) an enteropathy of unknown etiology was found in nearly one-third of the subjects, and 4) abnormalities in morphology did not necessarily mean presence of malabsorption.

Topics: Adolescent; Adult; Aged; Feces; Female; Humans; Intestinal Absorption; Intestinal Diseases, Parasitic; Intestine, Small; Iran; Lipid Metabolism; Male; Middle Aged; Nitrogen; Rural Population; Sprue, Tropical; Vitamin B 12; Xylose

Topics: Adolescent; Adult; Anemia; Anemia, Hypochromic; Blood Proteins; Deficiency Diseases; Erythrocytes; Female; Folic Acid; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Hematocrit; Hemoglobins; Humans; Intestinal Diseases, Parasitic; Iron; Iron Deficiencies; Lactation; Malaria; Male; Middle Aged; New Guinea; Pregnancy; Protein Binding; Sex Factors; Splenomegaly; Thalassemia; Vitamin B 12

Topics: Cobalt Isotopes; Deficiency Diseases; Dietary Fats; Dietary Proteins; Dominican Republic; Feces; Female; Humans; Intestinal Absorption; Intestinal Diseases; Intestinal Diseases, Parasitic; Intestines; Iron; Lipid Metabolism; Malabsorption Syndromes; Male; Nitrogen; Nutrition Disorders; Nutrition Surveys; Nutritional Physiological Phenomena; Pregnancy; Vitamin B 12; Xylose

Topics: Adolescent; Age Factors; Anemia; Anemia, Hypochromic; Ascariasis; Blood Proteins; Child; Deficiency Diseases; Female; Folic Acid; Folic Acid Deficiency; Hematocrit; Hemoglobinometry; Humans; Intestinal Diseases, Parasitic; Iron; Male; Philippines; Transferrin; Trichuriasis; Vitamin B 12; Vitamin B 12 Deficiency

Topics: Adolescent; Age Factors; Child; Child, Preschool; Digestive System; Helminthiasis; Humans; Intestinal Diseases, Parasitic; Intrinsic Factor; Vitamin B 12

Topics: Adolescent; Adult; Aged; Cobalt Isotopes; Female; Folic Acid; Humans; Intestinal Absorption; Intestinal Diseases, Parasitic; Male; Methods; Middle Aged; Opisthorchiasis; Thailand; Tritium; Vitamin B 12

Topics: Adolescent; Adult; Anemia; Anemia, Hypochromic; Anemia, Macrocytic; Bilirubin; Blood Cell Count; Blood Proteins; Child; Child, Preschool; Cholesterol; Diet Therapy; Female; Folic Acid; Folic Acid Deficiency; Health Surveys; Hematocrit; Hemoglobinometry; Humans; Intestinal Diseases, Parasitic; Iron; Male; Pregnancy; Pregnancy Complications, Hematologic; Trinidad and Tobago; Vitamin B 12

Topics: Animals; Body Weight; Cobalt; Coccidiosis; Hemoglobinometry; Intestinal Diseases, Parasitic; Leukocyte Count; Liver; Sheep; Sheep Diseases; Strongyloidiasis; Trichostrongyloidiasis; Vitamin B 12