vitamin-b-12 and Hypopituitarism

Topics: Adrenal Insufficiency; Anemia; Anemia, Aplastic; Anemia, Macrocytic; Conjunctivitis; Electrocardiography; Folic Acid; Heart Failure; Hepatitis; Hypertrichosis; Hypopituitarism; Hypothalamus; Leukopenia; Lymph Nodes; Metabolism; Methemoglobinemia; Pharmacology; Phenytoin; Pulmonary Fibrosis; Thrombocytopenia; Thyroid Function Tests; Toxicology; Vitamin B 12

A technique has been developed for accurately assaying serum and urine (57)Co cyanocobalamin during the conventional Schilling test. Serum and urine radioactivity in a large number of patients has been correlated and the precise normal limits have been determined by statistical analysis. The implications of this for investigating conditions other than pernicious anaemia and the malabsorption syndromes are stressed.

Topics: Chemistry Techniques, Analytical; Cobalt Isotopes; Folic Acid Deficiency; Humans; Hypopituitarism; Methods; Myxedema; Postgastrectomy Syndromes; Schilling Test; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency

An assessment of vitamin B(12) absorption in neurological patients has been made by both serum and urine counting of (57)Co cyanocobalamin during the conventional Schilling test. Although patients with pernicious anaemia, some with subacute combined degeneration of the cord, have been studied, emphasis in the discussion is placed on the significantly increased excretion of the radioactive vitamin in a group of patients with pituitary insufficiency. Results are also given for epileptic patients who have developed folate deficiency (as assessed by serum folate levels) coincidental with anticonvulsant therapy, as well as for some patients who have had neurological symptoms or signs following partial gastrectomy operations.

Topics: Adult; Aged; Anemia, Pernicious; Cobalt Isotopes; Epilepsy; Female; Folic Acid Deficiency; Humans; Hypopituitarism; Intestinal Absorption; Male; Middle Aged; Postgastrectomy Syndromes; Schilling Test; Vitamin B 12

Topics: Adolescent; Adrenal Gland Diseases; Adrenal Insufficiency; Adrenalectomy; Adult; Aged; Anemia, Pernicious; Antibodies; Antigens; Cobalt Isotopes; Cortisone; Cushing Syndrome; Female; Humans; Hypopituitarism; Intestinal Absorption; Intrinsic Factor; Malabsorption Syndromes; Male; Middle Aged; Vitamin B 12

Topics: Adolescent; Adrenocorticotropic Hormone; Child; Developmental Disabilities; Gonadotropins; Growth; Growth Disorders; Humans; Hypopituitarism; Ileum; Jejunum; Male; Postoperative Complications; Vitamin A; Vitamin B 12

Topics: Addison Disease; Glucose; Glucose Tolerance Test; Humans; Hypopituitarism; Intestinal Absorption; Malabsorption Syndromes; Myxedema; Vitamin B 12

Topics: Adolescent; Carnitine; Child; Drug Therapy; Folic Acid; Growth; Hypopituitarism; Lysine; Pharmacology; Pituitary Diseases; Vitamin B 12; Vitamin B Complex; Weight Gain