vitamin-b-12 and Hepatitis-B--Chronic

To develop a dietary methyl donor food frequency questionnaire (DMD-FFQ) that is validated in a cohort of US children and to determine whether the consumption of folate and vitamin B. We developed a semiquantitative DMD-FFQ to estimate intake of folate and vitamin B. Folate per kilogram of body weight by the DMD-FFQ correlated positively with 24-hour recall (r = 0.60; P < .001) and red blood cell folate (r = 0.40; P = .02), and negatively with homocysteine (r = -0.54; P < .001). Vitamin B. Our DMD-FFQ correlates well with a 24-hour recall and circulating biomarkers. Although little evidence existed that consumption of these micronutrients correlated with HBV replication, this tool could prove useful for investigating epigenetic modification by diet for several pediatric diseases.

Topics: Adolescent; Biomarkers; Child; Child, Preschool; CpG Islands; DNA Methylation; DNA, Viral; Epigenesis, Genetic; Erythrocytes; Female; Folic Acid; Hepatitis B virus; Hepatitis B, Chronic; Homocysteine; Humans; Male; Surveys and Questionnaires; Vitamin B 12