vitamin-b-12 and Facial-Dermatoses

Topics: Acne Vulgaris; Adult; Facial Dermatoses; Female; Humans; Neck; Vitamin B 12; Vitamin B Complex

Topics: Acneiform Eruptions; Adapalene; Adult; Benzoyl Peroxide; Brain Damage, Chronic; Brain Injuries; Clindamycin; Drug Therapy, Combination; Facial Dermatoses; Female; Humans; Lymecycline; Male; Naphthalenes; Vitamin B 12

Rosacea fulminans is a rare variant of rosacea conglobata that occurs almost exclusively in women well past adolescence. The aetiology is unknown, although immunological, hormonal, and vascular factors have been suggested. We report the case of a 17-year-old girl with rosacea fulminans that was temporally associated with daily ingestion of high-dose vitamin B supplements. The onset was sudden and cosmetically disabling. The eruption improved when the vitamin supplement was discontinued and a therapeutic regimen including isotretinoin and methylprednisolone was introduced. It seems appropriate to consider the possibility of such a vitamin B-triggered condition in cases of subjects presenting new or exacerbating facial eruptions.

Topics: Adolescent; Dietary Supplements; Dose-Response Relationship, Drug; Drug Eruptions; Facial Dermatoses; Female; Follow-Up Studies; Humans; Risk Assessment; Rosacea; Severity of Illness Index; Vitamin B 12; Vitamin B 6

Topics: Abetalipoproteinemia; Abnormalities, Multiple; Carbohydrate Metabolism, Inborn Errors; Dermatoglyphics; Dwarfism; Dysautonomia, Familial; Dystonia Musculorum Deformans; Facial Dermatoses; Factor XI Deficiency; Familial Mediterranean Fever; Gaucher Disease; Genetic Diseases, Inborn; Genetics, Population; Glucosephosphate Dehydrogenase Deficiency; Glycogen Storage Disease; Humans; Israel; Jaundice, Chronic Idiopathic; Jews; Lipidoses; Niemann-Pick Diseases; Pentoses; Phenylketonurias; Telangiectasis; Thalassemia; Vitamin B 12