vitamin-b-12 has been researched along with Bronchial-Spasm* in 2 studies
2 other study(ies) available for vitamin-b-12 and Bronchial-Spasm
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Rare sensory and autonomic disturbances associated with vitamin B12 deficiency.
Vitamin B12 deficiency is an important nutritional disorder causing neurological manifestations of myelopathy, neuropathy and dementia. Sub-acute combined degeneration (SCD) with involvement of the posterior columns in the cervical and thoracic cord is a common presentation of this disorder. In this case report, we describe a 43 year old woman with pernicious anemia and myelopathy with atypical clinical features. The patient presented with motor symptoms, a sensory level and bladder dysfunction. She had severe autonomic disturbances including an episode of unexplained bronchospasm, which has not been previously reported as a manifestation of vitamin B12 deficiency. We review the literature regarding these rarely reported features of vitamin B12 deficiency, and discuss aspects of management of this reversible condition. We emphasize the importance of awareness of autonomic disturbances in B12 deficient individuals. Topics: Adult; Anemia, Pernicious; Autonomic Nervous System Diseases; Bronchi; Bronchial Spasm; Female; Humans; Leg; Magnetic Resonance Imaging; Muscle, Skeletal; Neural Pathways; Paraparesis; Sensation Disorders; Spinal Cord; Spinal Cord Diseases; Subacute Combined Degeneration; Sympathetic Nervous System; Treatment Outcome; Urinary Bladder, Neurogenic; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Asthma with sulfite intolerance in children: a blocking study with cyanocobalamin.
Sulfites have been implicated as the cause of bronchospasm in some subjects with asthma. However, there is still no universally accepted explanation of the pathogenesis of these reactions. We have studied five children with asthma with metabisulfite intolerance confirmed by oral challenge testing. The challenge test with metabisulfite was repeated after premedication of all the patients with 1.5 mg of oral cyanocobalamin. In four of the five patients treated with cyanocobalamin, bronchospasm did not develop in the second metabisulfite challenge. The possible mechanisms are discussed. Topics: Administration, Oral; Adolescent; Asthma; Bronchial Spasm; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Evaluation; Drug Tolerance; Humans; Male; Single-Blind Method; Sulfites; Time Factors; Vitamin B 12 | 1992 |