vitamin-b-12 and Back-Pain

Topics: Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Drug Therapy, Combination; Humans; Thiamine; Vitamin B 12; Vitamin B Complex

Topics: Adult; Aminopyrine; Anesthetics, Local; Anti-Inflammatory Agents; Back Pain; Cauda Equina; Dexamethasone; Drug Combinations; Female; Humans; Injections; Lumbosacral Region; Male; Middle Aged; Pain; Paralysis; Pelvis; Phenylbutazone; Spinal Cord; Thiamine; Vitamin B 12

The case of a 42-year-old man is reported, who on four occasions developed a hypokalaemic periodic paralysis after an intramuscular injection of "Ambene". The detailed examination of this patient shows, that it is the primary, autosomal dominant inherited form of hypokalaemic periodic paralysis, and not the secondary form, which is caused by a renal or gastrointestinal loss of potassium. Clinical and electrophysiological, as well as histopathological and electron microscopic findings are presented, showing the typical vacuolar myopathy with submicroscopic tubular structures. In the literature there is evidence for an increased sensitivity of the muscle membrane to insulin with an increased potassium-shift inside the cell in hypokalaemic periodic paralysis. "Ambene" is a combination, which contains amongst other substances dexamethasone and the local anaesthetic drug lidocain. In the present case the paresis was possibly caused by a combined effect of dexamethasone with a consequent hyperglycaemia and lidocain with a change in the excitability of the muscle membrane. The pathophysiological mechanism of hypokalaemic periodic paralysis is discussed in terms of the release by the combination of these two drugs. It has not previously been reported that "Ambene" can provoke a hypokalaemic periodic paralysis. This is a severe side effect because of the resulting cardiac and respiratory problems.

Topics: Adult; Aminopyrine; Anti-Inflammatory Agents; Back Pain; Dexamethasone; Drug Combinations; Humans; Hypokalemia; Injections, Intramuscular; Male; Muscles; Paralyses, Familial Periodic; Phenylbutazone; Potassium; Thiamine; Vitamin B 12

Many patients complaining of acute pain in the lumbosacral area suffer from affections of intrapelvic organs (urinary bladder, prostate glands, female genital-organs). The routine diagnosis in such cases is described. In 53 own patients the analgesic and anti-inflammatory effect of Dolo-Neurobion has been evaluated. It is a combination drug consisting of the neurotropic vitamins B1, B6 and B12 and the analgesic metamizole. The treatment was started parenterally in the recommended doses and continued orally. If there were definite signs of infection in the pelvic area, additional antibiotics were administered after bacteriological tests. Dolo-Neurobion showed good or excellent results in 77,4% and moderate effects in 15,1% of the patients. There were no major side-effects or intolerance.

Topics: Aminopyrine; Back Pain; Dipyrone; Drug Combinations; Humans; Pyridoxine; Thiamine; Vitamin B 12

Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Back Pain; Cervical Vertebrae; Drug Combinations; Drug Evaluation; Flufenamic Acid; Humans; Joint Diseases; Male; Middle Aged; Palliative Care; Periarthritis; Pyridoxal; Spinal Osteophytosis; Thiamine; Vitamin B 12

Topics: Analgesics; Back Pain; Brachial Plexus Neuritis; Delayed-Action Preparations; Drug Combinations; Female; Humans; Lumbosacral Region; Male; Osteoarthritis; Periarthritis; Phantom Limb; Pyrazoles; Pyridoxine; Sulfonic Acids; Thiamine; Trigeminal Neuralgia; Vitamin B 12; Vitamin B Complex

Topics: Adenine Nucleotides; Adult; Aged; Back Pain; Cyclic AMP; Drug Combinations; Drug Tolerance; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Neuralgia; Neuritis; Sciatica; Thiamine; Thymine Nucleotides; Vitamin B 12

Topics: Adult; Anemia, Pernicious; Back Pain; Cobalt Isotopes; Female; Humans; Intestinal Absorption; Male; Middle Aged; Vitamin B 12

Topics: Adenine Nucleotides; Adult; Aged; Aminopyrine; Back Pain; Brachial Plexus Neuritis; Female; Glycerides; Humans; Male; Middle Aged; Neuralgia; Neuritis; Periarthritis; Sciatica; Suppositories; Thiamine; Vitamin B 12

Topics: Adenine Nucleotides; Adult; Aged; Aminopyrine; Back Pain; Brachial Plexus Neuritis; Female; Humans; Joint Diseases; Male; Middle Aged; Neuralgia; Sciatica; Thiamine; Vitamin B 12

Topics: Anesthesia, Conduction; Back Pain; Humans; Hydrocortisone; Intervertebral Disc Displacement; Lumbosacral Region; Procaine; Stellate Ganglion; Vitamin B 12

Topics: Adult; Aged; Back Pain; Female; Humans; Iontophoresis; Male; Methods; Middle Aged; Vitamin B 12

Topics: Back Pain; Brachial Plexus Neuritis; Corrinoids; Fractures, Bone; Hepatitis; Humans; Intervertebral Disc Displacement; Orthopedics; Pyridoxine; Sciatica; Syphilis; Thiamine; Traumatology; Vitamin B 12; Vitamin B Complex; Vitamins