vitamin-b-12 and Asthenia

vitamin-b-12 has been researched along with Asthenia* in 18 studies

Trials

1 trial(s) available for vitamin-b-12 and Asthenia

ArticleYear
[Biometric study on the behavior of various clinical signs taken as parameters of the effects of the various components of a combination of hepatovitaminic and adrenocortical factors].
    La Clinica terapeutica, 1970, Jul-15, Volume: 54, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Analysis of Variance; Asthenia; Bilirubin; Blood Pressure; Blood Proteins; Child; Clinical Trials as Topic; Dyspepsia; Feeding and Eating Disorders; Humans; Liver Extracts; Liver Function Tests; Middle Aged; Pyridoxine; Statistics as Topic; Vitamin B 12; Wit and Humor as Topic

1970

Other Studies

17 other study(ies) available for vitamin-b-12 and Asthenia

ArticleYear
A link between asthenia, pallor, and jaundice.
    BMJ (Clinical research ed.), 2016, Jun-07, Volume: 353

    Topics: Anemia, Pernicious; Asthenia; Disease Management; Humans; Jaundice; Male; Middle Aged; Pallor; Prognosis; Schilling Test; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex

2016
Food-cobalamin malabsorption in elderly patients: clinical manifestations and treatment.
    The American journal of medicine, 2005, Volume: 118, Issue:10

    Approximately 15% of people aged more than 60 years old have a cobalamin (vitamin B12) deficiency, mainly in relation with food-cobalamin malabsorption (FCM). To date, no study has documented this disorder in the elderly. There is also little information on clinical consequences.. We studied 92 elderly patients with well-established FCM who were extracted from an observational cohort study (1995-2004) of 172 consecutive elderly patients with documented cobalamin deficiency.. The median patient age was 76 +/- 8 years; 60 patients were women. The most common clinical manifestations were neurologic or psychologic: mild sensory polyneuropathy (44.6%), confusion or impaired mental functioning (22.8%), and physical asthenia (20.7%). Hematologic abnormalities were reported in at least one third of the patients: anemia (21%), leukopenia (10.9%), thrombopenia (8.7%), and pancytopenia (6.5%). All patients had low serum vitamin B12 levels (<200 pg/mL), with a mean value (+/- standard deviation) of 131 +/- 38 pg/mL and total serum homocysteine level of 22.1 +/- 9.3 micromol/L. The mean hemoglobin level was 10.9 +/- 2.5 g/dL and the mean erythrocyte cell volume 95.7 +/- 12.7 fL. Correction of the serum vitamin B12 levels and hematologic abnormalities was achieved equally well in patients treated with either intramuscular or oral crystalline cyanocobalamin.. This study suggests that in elderly patients, FCM may be associated with significant neurologic, psychologic, and hematologic abnormalities, which seem to respond equally well to either oral or parenteral vitamin B12 therapy.

    Topics: Aged; Aged, 80 and over; Asthenia; Cognition Disorders; Cohort Studies; Confusion; Edema; Erythrocyte Indices; Female; Follow-Up Studies; Gastritis, Atrophic; Hematologic Diseases; Hemoglobins; Homocysteine; Humans; Jaundice; Malabsorption Syndromes; Male; Paresthesia; Polyneuropathies; Reflex, Abnormal; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency

2005
[Vitamin B12 deficiency with normal Schilling test or non-dissociation of vitamin B12 and its carrier proteins in elderly patients. A study of 60 patients].
    La Revue de medecine interne, 2003, Volume: 24, Issue:4

    Approximately 15% of people over 60 years old have a cobalamin (Cbl) deficiency in relation with a food-cobalamin malabsorption (FCM). But to date, only case reports or small series have been reported. The aim of this study was to describe the clinical characteristics of the FCM in old subjects.. Sixty patients, at least 65 years old, presenting a Cbl deficiency related to FCM, were extracted from a cohort study of the Hôpitaux universitaires de Strasbourg, France (n = 169). All these patients had an established diagnosis of Cbl deficiency and met the Carmel's criteria of FCM. Their clinical data were retrospectively analysed.. The median age of the 60 patients was 75 years and the female/male ratio was 2.3. The principal clinical symptoms were peripheral neuropathy (35%), confusion and dementia (30%) and anemia-related manifestations such as asthenia and edemas of the legs (20%). Average hemoglobin was 10.7 +/- 2.5 g/dl and average mean erythrocyte cell volume was 95.5 +/- 13.8 fl. There was an anemia, a leucopenia, a thrombocytopenia and a pancytopenia in respectively 27%, 18%, 15% and 8% of the cases. Average serum vitamin B(12) and homocystein levels were with 138 +/- 42 pg/ml and 22.5 +/- 15.2 micro mol/l. No patient had anti-intrinsic factor antibody and the Schilling's test was normal in all patients. Main disorders associated with FCM were atrophic gastritis (59%), long-term metformin or antiacid intake (17%), chronic alcohol intake (8%) and idiopathic FCM (n = 10). Sixteen patients have been successfully treated with oral crystalline cyanocobalamin (500 +/- 280 micro g/d).. This study shows that: firstly, the Cbl deficiency related to FCM may be responsible of severe neurological and hematologic manifestations in approximately 20% of the elderly patients; secondly, the disorders associated with the FCM are multiple in old age, with mainly atrophic gastritis; and thirdly, in clinical practice, oral cyanoCbl treatment may be successful.

    Topics: Administration, Oral; Age Distribution; Aged; Aged, 80 and over; Asthenia; Carrier Proteins; Cohort Studies; Confusion; Diagnosis, Differential; Female; Food-Drug Interactions; France; Humans; Malabsorption Syndromes; Male; Middle Aged; Peripheral Nervous System Diseases; Retrospective Studies; Schilling Test; Sex Distribution; Vitamin B 12; Vitamin B 12 Deficiency

2003
[Uremic neuropathy: clinical evolution and therapeutic results in a 5-year period of observation].
    Giornale di clinica medica, 1982, Volume: 63, Issue:1

    Topics: Adult; Aged; Asthenia; Calcitonin; Female; Gangliosides; Humans; Kidney Transplantation; Male; Middle Aged; Nervous System Diseases; Paresthesia; Renal Dialysis; Restless Legs Syndrome; Uremia; Vitamin B 12

1982
Understanding the uremic syndrome through hemodialysis.
    Biomaterials, medical devices, and artificial organs, 1974, Volume: 2, Issue:4

    Topics: Acrylates; Adult; Anemia; Asthenia; Calcium; Chemical Phenomena; Chemistry, Physical; Creatinine; Female; Filtration; Humans; Kidneys, Artificial; Male; Membranes, Artificial; Middle Aged; Molecular Weight; Nitriles; Peritoneal Dialysis; Permeability; Polyneuropathies; Renal Dialysis; Succinates; Time Factors; Urea; Uremia; Uric Acid; Vitamin B 12

1974
Experimental nutritional folate deficiency in the baboon (Papio cynocephalus).
    The British journal of nutrition, 1974, Volume: 32, Issue:3

    Topics: Anemia, Macrocytic; Animals; Asthenia; Body Weight; Diarrhea; Feeding and Eating Disorders; FIGLU Test; Folic Acid; Folic Acid Deficiency; Gingivitis; Humans; Leukopenia; Liver; Male; Malonates; Papio; Thrombocytopenia; Vitamin B 12

1974
[Controlled clinico-statistical studies on the role of the nucleosides in an association of hepatoprotective and anti-asthenic action].
    Minerva medica, 1974, Feb-03, Volume: 65, Issue:8

    Topics: Adenosine; Adrenal Glands; Adult; Aged; Asthenia; Cytidine; Drug Combinations; Female; Guanosine; Hepatitis A; Humans; Liver; Liver Diseases; Liver Extracts; Liver Function Tests; Male; Middle Aged; Nucleosides; Tissue Extracts; Uridine; Vitamin B 12

1974
[Clinical test of the therapeutic effectiveness of hepatic opotherapy associated with high doses of nucleosides].
    Minerva medica, 1972, Jun-09, Volume: 63, Issue:44

    Topics: Adult; Aged; Anemia; Asthenia; Body Weight; Cachexia; Chronic Disease; Cytidine; Diabetes Complications; Female; Heart Diseases; Humans; Hyperthyroidism; Liver Diseases; Liver Extracts; Male; Middle Aged; Nucleosides; Uridine; Vitamin B 12

1972
[Asthenic states and one of their modern treatments].
    Therapeutique (La Semaine des hopitaux), 1972, Volume: 48, Issue:4

    Topics: Adjustment Disorders; Adrenal Cortex Hormones; Adult; Aged; Asthenia; Diabetes Complications; DNA; Drug Combinations; Female; Humans; Intrinsic Factor; Male; Middle Aged; Neurasthenia; Vitamin B 12

1972
[Clinical evaluation of a non-hormonic anabolizing agent, adenosylcobamide, a coenzyme of vitamin B 12, in geriatrics].
    Giornale di gerontologia, 1970, Volume: 18, Issue:2

    Topics: Age Factors; Aged; Asthenia; Blood Proteins; Body Weight; Coenzymes; Feeding and Eating Disorders; Humans; Metabolism; Vitamin B 12

1970
[Clinical testing of the validity of a treatment with a base of adrenal cortex extract in combination with hematoporphyrin and vitamin factors in some adynamic syndromes].
    La Clinica terapeutica, 1969, Sep-15, Volume: 50, Issue:5

    Topics: Adjustment Disorders; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Asthenia; Biliary Tract Diseases; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hypotension; Leukemia; Lung Diseases; Male; Middle Aged; Porphyrins; Pyridoxine; Urologic Diseases; Vitamin B 12

1969
[Results of the oral administration of a compound of amino acids with hydroxocobalamin in a series of aged subjects].
    La Clinica terapeutica, 1968, Sep-15, Volume: 46, Issue:5

    Topics: Aged; Amino Acids; Asthenia; Dementia; Depression; Female; Humans; Male; Memory Disorders; Protein Deficiency; Vitamin B 12

1968
[Use of 5,6-dimethylbenzimidazole-cobamide coenzyme (Indusil) in 31 adult patients].
    Semaine therapeutique, 1965, Volume: 41, Issue:9

    Topics: Adult; Aged; Asthenia; Coenzymes; Deficiency Diseases; Emaciation; Humans; Liver Diseases; Middle Aged; Neoplasms; Respiratory Tract Diseases; Vitamin B 12

1965
[APROPOS OF THE CLINICAL INDICATIONS OF A NEW DRINKABLE ENRICHED LIVER EXTRACT OF THE ANTITOXIC FRACTION].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1964, Volume: 141

    Topics: Alcoholic Intoxication; Alcoholism; Anemia; Aspartic Acid; Asthenia; Humans; Liver Cirrhosis; Liver Diseases; Liver Extracts; Magnesium; Nutrition Disorders; Postoperative Care; Potassium; Vitamin B 12; Yeast, Dried

1964
[Value of combined vitamins and amino acids in therapy of asthenia].
    Gazette medicale de France, 1959, Feb-25, Volume: 66, Issue:4

    Topics: Amino Acids; Ascorbic Acid; Asthenia; Corrinoids; Glycine; Hematinics; Humans; Vitamin A; Vitamin B 12; Vitamin K; Vitamins

1959
[Therapeutic effectiveness of a new preparation with psycho-tonic activity].
    Il Policlinico. Sezione pratica, 1959, Mar-09, Volume: 66, Issue:10

    Topics: Amino Alcohols; Asthenia; Corrinoids; Depression; Humans; Niacin; Nicotinic Acids; Vitamin B 12; Vitamin B 6; Vitamin B Complex

1959
[Intensive vitamin B1-B12 therapy in pains & asthenia].
    Semaine medicale professionelle et medico-sociale, 1958, Dec-30, Volume: 34, Issue:45

    Topics: Asthenia; Folic Acid; Humans; Pain Management; Thiamine; Vitamin B 12; Vitamin B Complex

1958