vinzolidine has been researched along with Hodgkin-Disease* in 1 studies
1 other study(ies) available for vinzolidine and Hodgkin-Disease
Article | Year |
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Phase II trial of vinzolidine, an oral vinca alkaloid, in Hodgkin's disease and non-Hodgkin's lymphoma.
Vinzolidine, a semisynthetic vinblastine derivative, was tested in an oral formulation in 21 heavily pretreated patients with lymphoma. Partial remissions were seen in four patients with Hodgkin's disease (50%) and in one patient with non-Hodgkin's lymphoma (8%). Significant side effects included neurotoxicity and dose-related myelosuppression. Vinzolidine is an active vinca alkaloid which merits further evaluation in patients with lymphoma, particularly Hodgkin's disease. Topics: Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Hodgkin Disease; Humans; Lymphoma; Male; Middle Aged; Vinca Alkaloids | 1984 |