Page last updated: 2024-08-17

vinyl chloride and Hepatocellular Carcinoma

vinyl chloride has been researched along with Hepatocellular Carcinoma in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199018 (41.86)18.7374
1990's8 (18.60)18.2507
2000's9 (20.93)29.6817
2010's6 (13.95)24.3611
2020's2 (4.65)2.80

Authors

AuthorsStudies
Althouse, AD; Arteel, GE; Bannister, OB; Beier, JI; Cave, MC; He, L; Li, J; Liu, S; Monga, SP; Schnegelberger, RD; Schopfer, FJ; Vanderpuye, CM; Wahlang, B; Zhang, X1
Hu, J; Jia, J; Jie, L; Pan, W; Qiu, Y; Wang, Q; Yan, X; Yu, S; Zhang, P1
Zhao, X; Zhou, G1
Baccini, M; Ballarin, MN; Comba, P; Fedeli, U; Gardiman, G; Girardi, P; Mastrangelo, G; Pirastu, R; Scoizzato, L; Zara, D1
Fassan, M; Guido, M; Murer, B; Pelletti, G; Sarcognato, S; Snenghi, R1
Lotti, M1
Dragani, TA; Zocchetti, C1
Fedeli, U; Martines, D; Mastrangelo, G2
Sherman, M1
Fedeli, U; Mastroangelo, G1
Agnesi, R; Buda, A; Fadda, E; Fedeli, U; Magarotto, G; Marchì, T; Martines, D; Mastrangelo, G; Pinzani, M; Valentini, F1
Tamburro, CH1
Evans, DM; Kung, IT; Williams, WJ1
Hermanutz, D; Koischwitz, D; Lackner, K; Lelbach, WK1
Dannaher, CL; Tamburro, CH; Yam, LT1
Bingham, E; Radike, MJ; Stemmer, KL1
Dietz, A; Langbein, G; Permanetter, W2
Harris, CC; Hollstein, M; Kusters, I; Lehman, T; Marion, MJ; Martel-Planche, G; Montesano, R; Welsh, J1
Lelbach, WK1
Brandt-Rauf, P; Luo, JC; Marion, MJ; Smith, SJ1
Brandt-Rauf, PW; De Vivo, I; Luo, JC; Marion, MJ; Smith, S1
Ando, Y; Makita, O; Ono, K; Sakurai, T; Takahashi, M; Tanigawa, H; Yamashita, K; Yoshimatsu, M1
Berger, F; Jacob, P; Mion, F; Paliard, P; Partensky, C; Saurin, JC; Tanière, P1
Boivin-Angele, S; Marion, MJ1
Bancel, B; Barbin, A; Bartsch, H; Bogdanffy, MS; Boivin-Angèle, S; Froment, O; Lefrançois, L; Marion, MJ; Spiethoff, A; Swenberg, J; Trépo, C; Wegener, K; Wesch, H1
Köckerling, F; Lehnert, G; Tannapfel, A; Weihrauch, M; Wittekind, C1
Aitio, A; Kielhorn, J; Mangelsdorf, I; Melber, C; Wahnschaffe, U1
Benicke, M; Lehnert, G; Tannapfel, A; Weihrauch, M; Wittekind, C; Wrbitzky, R1
Bader, M; Benick, M; Lehner, G; Tannapfel, A; Weihrauch, M; Wittekind, M; Wrbitzk, R1
Anthony, PP1
Horak, W; Polterauer, P1
Eder, M; Gokel, JM; Liebezeit, E1
Popper, H2
Rudolph, RH1
Delorme, F1
Beamer, P; Callaghan, O; Hazdra, JJ; Keith, L; Nair, V1
Kopp, N; Pahn, M; Pasquier, B; Pialat, J1
Comba, P; Foa, V; Maltoni, C; Masina, A; Pirastu, R; Reggiani, A1
Chieco, P; Maltoni, C; Moslen, MT; Normanni, P1
Masuda, Y; Sugita, M; Tsuchiya, K1

Reviews

6 review(s) available for vinyl chloride and Hepatocellular Carcinoma

ArticleYear
Do occupational exposures to vinyl chloride cause hepatocellular carcinoma and cirrhosis?
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37, Issue:5

    Topics: Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neoplasms; Multicenter Studies as Topic; Occupational Exposure; Risk Factors; Vinyl Chloride

2017
Vinyl chloride and the liver.
    Journal of hepatology, 2009, Volume: 51, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Hemangiosarcoma; Humans; Liver; Liver Cirrhosis; Liver Neoplasms; Mutagens; Occupational Exposure; Risk Factors; Vinyl Chloride

2009
Relationship of vinyl monomers and liver cancers: angiosarcoma and hepatocellular carcinoma.
    Seminars in liver disease, 1984, Volume: 4, Issue:2

    Topics: Carcinoma, Hepatocellular; Chemical Industry; Diagnosis, Differential; Dose-Response Relationship, Drug; Hemangiosarcoma; Humans; Liver; Liver Neoplasms; Occupational Diseases; Vinyl Chloride; Vinyl Compounds

1984
Vinyl chloride: still a cause for concern.
    Environmental health perspectives, 2000, Volume: 108, Issue:7

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Environmental Exposure; Epidemiologic Studies; Hemangiosarcoma; Humans; Liver Neoplasms; Occupational Exposure; Rats; Risk Assessment; Vinyl Chloride

2000
Hepatic cancers in man: quantitative perspectives.
    Environmental research, 1979, Volume: 19, Issue:2

    Topics: Adenoma, Bile Duct; Alcoholism; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Epidemiologic Methods; Gonadal Steroid Hormones; Hepatitis B; Humans; Liver Neoplasms; Vinyl Chloride

1979
[Hepatic lesions caused by vinyl chloride monomer in humans. Study of eight clinicopathological cases (author's transl)].
    Archives d'anatomie et de cytologie pathologiques, 1979, Volume: 27, Issue:6

    Topics: Adult; Carcinogens; Carcinoma, Hepatocellular; Hemangiosarcoma; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Mutagens; Occupational Diseases; Vinyl Chloride; Vinyl Compounds

1979

Other Studies

37 other study(ies) available for vinyl chloride and Hepatocellular Carcinoma

ArticleYear
Western diet unmasks transient low-level vinyl chloride-induced tumorigenesis; potential role of the (epi-)transcriptome.
    Toxicology and applied pharmacology, 2023, 06-01, Volume: 468

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diet, Western; Liver; Liver Neoplasms; Mice; Non-alcoholic Fatty Liver Disease; Transcriptome; Vinyl Chloride

2023
Deregulation of the cell cycle and related microRNA expression induced by vinyl chloride monomer in the hepatocytes of rats.
    Toxicology and industrial health, 2021, Volume: 37, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Cell Cycle; Gene Expression Profiling; Hepatocytes; Humans; Liver Neoplasms; MicroRNAs; Models, Animal; Rats; Vinyl Chloride

2021
Carcinogens that induce the A:T > T:A nucleotide substitutions in the genome.
    Frontiers of medicine, 2018, Volume: 12, Issue:2

    Topics: Aristolochic Acids; Carcinogens; Carcinoma, Hepatocellular; China; Environment; Humans; Liver Neoplasms; Mutation; Nicotiana; Taiwan; Vinyl Chloride

2018
Mortality from liver angiosarcoma, hepatocellular carcinoma, and cirrhosis among vinyl chloride workers.
    American journal of industrial medicine, 2019, Volume: 62, Issue:1

    Topics: Adult; Carcinoma, Hepatocellular; Cause of Death; Cohort Studies; Female; Hemangiosarcoma; Humans; Italy; Liver Cirrhosis; Liver Neoplasms; Male; Occupational Diseases; Occupational Exposure; Poisson Distribution; Vinyl Chloride; Young Adult

2019
Sequential development of hepatocellular carcinoma and liver angiosarcoma in a vinyl chloride-exposed worker.
    Human pathology, 2016, Volume: 57

    Topics: Aged; Antigens, CD34; Biomarkers, Tumor; Biopsy; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; DNA Mutational Analysis; Hemangiosarcoma; Hepatectomy; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Male; Micronuclei, Chromosome-Defective; Occupational Diseases; Occupational Exposure; Point Mutation; Proto-Oncogene Proteins p21(ras); Vinyl Chloride

2016
Occupational exposure to vinyl chloride and risk of hepatocellular carcinoma.
    Cancer causes & control : CCC, 2008, Volume: 19, Issue:10

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Humans; Inhalation Exposure; Liver Neoplasms; Mice; Occupational Exposure; Rats; Risk Factors; Species Specificity; Vinyl Chloride

2008
Hepatocellular carcinoma and vinyl chloride.
    Cancer causes & control : CCC, 2009, Volume: 20, Issue:4

    Topics: Alcohol Drinking; Carcinogens; Carcinoma, Hepatocellular; Case-Control Studies; Confidence Intervals; Confounding Factors, Epidemiologic; Dose-Response Relationship, Drug; Drug Synergism; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Inhalation Exposure; Liver Neoplasms; Logistic Models; Occupational Exposure; Odds Ratio; Risk Factors; Vinyl Chloride

2009
Vinyl chloride and the liver: misrepresentation of epidemiological evidence.
    Journal of hepatology, 2010, Volume: 52, Issue:5

    Topics: Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Reproducibility of Results; Vinyl Chloride

2010
Vinyl chloride industry in the courtroom and corporate influences on the scientific literature.
    American journal of industrial medicine, 2011, Volume: 54, Issue:6

    Topics: Carcinoma, Hepatocellular; Chemical Industry; Conflict of Interest; Ethics, Research; Government Regulation; Hemangiosarcoma; Humans; Italy; Liver Neoplasms; Research; Research Support as Topic; Vinyl Chloride

2011
Increased risk of hepatocellular carcinoma and liver cirrhosis in vinyl chloride workers: synergistic effect of occupational exposure with alcohol intake.
    Environmental health perspectives, 2004, Volume: 112, Issue:11

    Topics: Aged; Alcohol Drinking; Carcinogens; Carcinoma, Hepatocellular; Case-Control Studies; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Occupational Exposure; Odds Ratio; Risk Assessment; Risk Factors; Vinyl Chloride

2004
Angiosarcoma and hepatocellular carcinoma in vinyl chloride workers.
    Histopathology, 1983, Volume: 7, Issue:3

    Topics: Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Hemangiosarcoma; Humans; Hyperplasia; Liver; Liver Neoplasms; Male; Middle Aged; Occupational Diseases; Time Factors; Vinyl Chloride; Vinyl Compounds

1983
[Vinyl chloride-induced angiosarcoma and hepato-cellular carcinoma of the liver (author's transl)].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1981, Volume: 134, Issue:3

    Topics: Angiography; Carcinoma, Hepatocellular; Hemangiosarcoma; Humans; Liver Neoplasms; Male; Middle Aged; Occupational Diseases; Polyvinyl Chloride; Vinyl Chloride; Vinyl Compounds

1981
Chemotherapy of vinyl chloride-associated hepatic angiosarcoma.
    Cancer, 1981, Feb-01, Volume: 47, Issue:3

    Topics: Adult; Carcinoma, Hepatocellular; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Hemangiosarcoma; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Occupational Diseases; Vinyl Chloride; Vinyl Compounds

1981
Effect of ethanol on vinyl chloride carcinogenesis.
    Environmental health perspectives, 1981, Volume: 41

    Topics: Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Ethanol; Hemangiosarcoma; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds

1981
[Hepatocellular carcinoma after exposure to vinyl chloride].
    Deutsche medizinische Wochenschrift (1946), 1983, May-13, Volume: 108, Issue:19

    Topics: Ascites; Carcinoma, Hepatocellular; Humans; Hypertension, Portal; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Occupational Diseases; Vinyl Chloride; Vinyl Compounds

1983
p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers.
    Carcinogenesis, 1994, Volume: 15, Issue:1

    Topics: Adenine; Aged; Base Composition; Base Sequence; Carcinoma, Hepatocellular; DNA; Exons; Gene Amplification; Genes, p53; Hemangiosarcoma; Humans; Liver Neoplasms; Middle Aged; Mutation; Neoplasm Proteins; Nuclear Proteins; Occupational Diseases; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Thymidine; Vinyl Chloride

1994
A 25-year follow-up study of heavily exposed vinyl chloride workers in Germany.
    American journal of industrial medicine, 1996, Volume: 29, Issue:5

    Topics: Adult; Carcinoma, Hepatocellular; Follow-Up Studies; Germany; Hemangiosarcoma; Humans; Liver Neoplasms; Male; Occupational Diseases; Occupational Exposure; Time Factors; Vinyl Chloride

1996
Mutant p53 protein as a biomarker of chemical carcinogenesis in humans.
    Journal of occupational and environmental medicine, 1996, Volume: 38, Issue:8

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Enzyme-Linked Immunosorbent Assay; Hemangiosarcoma; Humans; Liver Neoplasms; Occupational Diseases; Point Mutation; Tumor Suppressor Protein p53; Vinyl Chloride

1996
The molecular epidemiology of occupational carcinogenesis in vinyl chloride exposed workers.
    International archives of occupational and environmental health, 1996, Volume: 68, Issue:6

    Topics: Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cohort Studies; DNA, Neoplasm; Dose-Response Relationship, Drug; France; Gene Expression Regulation, Neoplastic; Genes, ras; Hemangiosarcoma; Humans; Liver Neoplasms; Logistic Models; Male; Middle Aged; Molecular Epidemiology; Occupational Diseases; Proto-Oncogene Proteins; Vinyl Chloride

1996
[A case of hepatocellular carcinoma related with exposure to vinyl chloride monomers].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1997, Volume: 94, Issue:3

    Topics: Air Pollutants, Occupational; Carcinogens; Carcinoma, Hepatocellular; Chemical Industry; Humans; Liver Neoplasms; Macromolecular Substances; Male; Middle Aged; Occupational Exposure; Vinyl Chloride

1997
Primary hepatocellular carcinoma in workers exposed to vinyl chloride: a report of two cases.
    Cancer, 1997, May-01, Volume: 79, Issue:9

    Topics: Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Middle Aged; Occupational Diseases; Vinyl Chloride

1997
Vinyl chloride-specific mutations in humans and animals.
    IARC scientific publications, 1999, Issue:150

    Topics: Alleles; Animals; Carcinogens; Carcinoma, Hepatocellular; Genes, ras; Hemangiosarcoma; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Sprague-Dawley; Thorium Dioxide; Vinyl Chloride

1999
Ras gene mutations in vinyl chloride-induced liver tumours are carcinogen-specific but vary with cell type and species.
    International journal of cancer, 2000, Jan-15, Volume: 85, Issue:2

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; DNA Mutational Analysis; Exons; Female; Genes, ras; Hemangiosarcoma; Liver Neoplasms; Male; Mice; Mutagenesis; Mutagens; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Sprague-Dawley; Thorium Dioxide; Vinyl Chloride; Vinyl Compounds

2000
p53 mutation pattern in hepatocellular carcinoma in workers exposed to vinyl chloride.
    Cancer, 2000, Mar-01, Volume: 88, Issue:5

    Topics: Aged; Amino Acid Substitution; Carcinogens; Carcinoma, Hepatocellular; Genes, p53; Humans; Liver Neoplasms; Middle Aged; Mutation; Occupational Exposure; Point Mutation; Vinyl Chloride

2000
Frequent k- ras -2 mutations and p16(INK4A)methylation in hepatocellular carcinomas in workers exposed to vinyl chloride.
    British journal of cancer, 2001, Apr-06, Volume: 84, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Carcinogens; Carcinoma, Hepatocellular; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Genes, p16; Genes, ras; Humans; Liver Neoplasms; Male; Middle Aged; Occupational Diseases; Point Mutation; Vinyl Chloride

2001
High prevalence of K-ras-2 mutations in hepatocellular carcinomas in workers exposed to vinyl chloride.
    International archives of occupational and environmental health, 2001, Volume: 74, Issue:6

    Topics: Adult; Aged; Base Sequence; Carcinoma, Hepatocellular; DNA Primers; Genes, ras; Germany; Humans; Immunohistochemistry; Liver Neoplasms; Middle Aged; Mutation; Occupational Exposure; Prevalence; Vinyl Chloride

2001
Primary carcinoma of the liver.
    Annals of the Royal College of Surgeons of England, 1976, Volume: 58, Issue:4

    Topics: Adenoma, Bile Duct; Adolescent; Aflatoxins; Africa; alpha-Fetoproteins; Asia, Eastern; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Female; Hepatitis A; Hepatitis B virus; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Steroids; Thorium Dioxide; Vinyl Chloride

1976
[Primary liver cell carcinoma, aetiology and clinical picture (author's transl)].
    Wiener klinische Wochenschrift, 1979, Aug-31, Volume: 91, Issue:16

    Topics: Adrenal Gland Neoplasms; Aflatoxins; alpha 1-Antitrypsin Deficiency; alpha-Fetoproteins; Androgens; Bone Neoplasms; Carcinogens; Carcinoma, Hepatocellular; Contraceptives, Oral, Hormonal; Female; Hepatitis B Antigens; Humans; Immunosuppression Therapy; Liver Cirrhosis; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasms, Radiation-Induced; Occupational Medicine; Parasitic Diseases; Portal Vein; Thrombosis; Vinyl Chloride

1979
Hemangiosarcoma and hepatocellular carcinoma of the liver following vinyl chloride exposure. A report of two cases.
    Virchows Archiv. A, Pathological anatomy and histology, 1976, Dec-27, Volume: 372, Issue:3

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Hemangiosarcoma; Humans; Liver Neoplasms; Male; Occupational Diseases; Vinyl Chloride; Vinyl Compounds

1976
[Liver tumors caused by environmental factors].
    Der Internist, 1977, Volume: 18, Issue:4

    Topics: Anabolic Agents; Animals; Arsenic; Carcinoma, Hepatocellular; Contraceptives, Oral; Environmental Exposure; Environmental Health; Female; Hemangiosarcoma; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Neoplasms, Experimental; Occupational Diseases; Precancerous Conditions; Rodentia; Thorium Dioxide; Vinyl Chloride

1977
Benign and malignant liver neoplasms: some new etiologic associations.
    Postgraduate medicine, 1978, Volume: 63, Issue:3

    Topics: Androgens; Carcinoma, Hepatocellular; Contraceptives, Oral; Female; Hemangiosarcoma; Hepatitis B virus; Humans; Liver Neoplasms; Male; Oncogenic Viruses; Vinyl Chloride

1978
[Association of angiosarcoma of the liver and hepatoma in vinyl chloride worker].
    Annales d'anatomie pathologique, 1978, Volume: 23, Issue:2

    Topics: Carcinoma, Hepatocellular; Environmental Exposure; Hemangiosarcoma; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Neoplasms, Multiple Primary; Occupational Diseases; Vinyl Chloride; Vinyl Compounds

1978
Chemical pollutants in relation to diseases in fish.
    Annals of the New York Academy of Sciences, 1978, Sep-29, Volume: 298

    Topics: Animals; Bacterial Infections; Carcinoma, Hepatocellular; Fish Diseases; Fishes; Helminthiasis, Animal; Kidney Diseases; Liver Neoplasms; Lymphoma; Mycoses; Myxococcales; Sepsis; Vinyl Chloride; Virus Diseases; Water Pollutants; Water Pollutants, Chemical

1978
Mortality from liver disease among Italian vinyl chloride monomer/polyvinyl chloride manufacturers.
    American journal of industrial medicine, 1990, Volume: 17, Issue:2

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Female; Hemangiosarcoma; Humans; Italy; Liver Neoplasms; Middle Aged; Occupational Diseases; Polyvinyl Chloride; Polyvinyls; Vinyl Chloride; Vinyl Compounds

1990
[Vinyl chloride induced hepatocellular carcinoma].
    Klinische Wochenschrift, 1985, Apr-01, Volume: 63, Issue:7

    Topics: Aged; Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Occupational Diseases; Vinyl Chloride; Vinyl Compounds

1985
Quantitative histochemistry of benzaldehyde dehydrogenase in hepatocellular carcinomas of vinyl chloride-treated rats.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1986, Volume: 34, Issue:2

    Topics: Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Benzaldehyde Dehydrogenase (NADP+); Benzaldehydes; Carcinoma, Hepatocellular; Disulfiram; Female; Histocytochemistry; Liver Neoplasms; Liver Neoplasms, Experimental; Male; NAD; NADP; Rats; Rats, Inbred Strains; Vinyl Chloride

1986
Early detection and signs of hepatoangiosarcoma among vinyl chloride workers.
    American journal of industrial medicine, 1986, Volume: 10, Issue:4

    Topics: Adult; Carcinoma, Hepatocellular; Female; Hemangiosarcoma; Humans; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Occupational Diseases; Vinyl Chloride; Vinyl Compounds

1986