vinpocetine and Disease Models, Animal

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

Topics: Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Cyclic Nucleotide Phosphodiesterases, Type 7; Disease Models, Animal; Female; Humans; Imidazoles; Inflammation; Male; Mice, Inbred BALB C; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pyridines; Rats, Wistar

Topics: Animals; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Humans; Immunoglobulin E; Mice; Mice, Hairless; Skin; Vinca Alkaloids

Topics: alpha-Synuclein; Animals; Disease Models, Animal; Male; Neurodegenerative Diseases; Neuroinflammatory Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone

Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Disks Large Homolog 4 Protein; Ketamine; Male; Neuroprotective Agents; Rats; Schizophrenia; Synapses; Vinca Alkaloids

Topics: Animals; Cell Line; Deubiquitinating Enzyme CYLD; Disease Models, Animal; Ear, Middle; Epithelial Cells; Gene Knockdown Techniques; Humans; MAP Kinase Signaling System; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Otitis Media; Pneumococcal Infections; RNA, Small Interfering; Streptococcus pneumoniae; Up-Regulation; Vinca Alkaloids

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cyclic Nucleotide Phosphodiesterases, Type 1; Disease Models, Animal; Glutathione; Injections, Intraventricular; Learning; Malondialdehyde; Memory; Memory Disorders; Morris Water Maze Test; Nitrites; Oxidative Stress; Phosphodiesterase Inhibitors; Rats; Spatial Memory; Vinca Alkaloids

Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arginine; Biomarkers; Disease Models, Animal; Inflammation Mediators; Male; NF-E2-Related Factor 2; Oxidative Stress; Pancreas; Pancreatitis; Rats, Wistar; Signal Transduction; Sirtuin 1; Tumor Necrosis Factor-alpha; Vinca Alkaloids

Topics: Animals; Anti-Inflammatory Agents; Brain; Disease Models, Animal; Infarction, Middle Cerebral Artery; Inflammasomes; Inflammation Mediators; Interleukin-18; Interleukin-1beta; Ischemic Stroke; Male; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Vinca Alkaloids

Topics: 1-Methyl-3-isobutylxanthine; Animals; Anti-Inflammatory Agents; Asthma; Chemokine CCL4; Dexamethasone; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; Lung; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Random Allocation; Vinca Alkaloids

Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Biomarkers; Disease Models, Animal; Doublecortin Protein; Female; Inflammation; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Valproic Acid; Vinca Alkaloids

Topics: Angiotensin II; Animals; Cardiomegaly; Cardiomyopathies; Cell Proliferation; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 1; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphodiesterase Inhibitors; Signal Transduction; Ventricular Remodeling; Vinca Alkaloids

Topics: Animals; Blood Glucose; Body Weight; Diabetic Nephropathies; Disease Models, Animal; Fasting; Gene Expression Regulation; Glycated Hemoglobin; Intracellular Signaling Peptides and Proteins; Kidney; Male; Membrane Proteins; NF-kappa B; Podocytes; Proteinuria; rac1 GTP-Binding Protein; Rats; Rats, Wistar; RNA, Messenger; Vinca Alkaloids

Topics: Animals; Calbindin 2; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Ischemia; Kainic Acid; Neuroprotective Agents; Parvalbumins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retinal Diseases; Retinal Neurons; Retinal Vessels; Vinca Alkaloids

Topics: Animals; Anthelmintics; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Resistance; Female; Immunohistochemistry; Isosorbide Dinitrate; Mice; Schistosoma mansoni; Schistosomiasis mansoni; Vinca Alkaloids

Topics: Analgesics; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Drug Repositioning; Edema; Heme Oxygenase-1; Hyperalgesia; Inflammation; Male; Membrane Proteins; Mice; NF-E2-Related Factor 2; NF-kappa B; Nootropic Agents; Oxidative Stress; Reactive Oxygen Species; Superoxides; Vinca Alkaloids

Topics: Animals; Disease Models, Animal; Graft Survival; Immunohistochemistry; Male; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury; Sensitivity and Specificity; Skin Transplantation; Superoxide Dismutase; Surgical Flaps; Vascular Endothelial Growth Factor A; Vinca Alkaloids

Topics: Animals; Apolipoproteins E; Atherosclerosis; Cyclic Nucleotide Phosphodiesterases, Type 1; Disease Models, Animal; Disease Progression; Foam Cells; Humans; I-kappa B Proteins; Inflammation; Lipoproteins, LDL; Male; Mice; Mice, Knockout; Monocytes; NF-kappa B; Oxidative Stress; Phosphorylation; Plaque, Atherosclerotic; Proto-Oncogene Proteins c-akt; Signal Transduction; Vinca Alkaloids

Topics: Animals; Cell Death; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Electroretinography; Energy Metabolism; Ependymoglial Cells; Evoked Potentials; Glucose; Glutamic Acid; Ischemia; L-Lactate Dehydrogenase; Neuroprotective Agents; Rats, Sprague-Dawley; Retinal Diseases; Tissue Culture Techniques; Vinca Alkaloids

Topics: Animals; Cell Line; Disease Models, Animal; Dual Specificity Phosphatase 1; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Mice; Mucin 5AC; Otitis Media; Pneumococcal Infections; Streptococcus pneumoniae; Vinca Alkaloids

Topics: Acetamides; Acetylcholinesterase; Analysis of Variance; Animals; Arterial Occlusive Diseases; Brain; Catalase; Dementia, Vascular; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Male; Malondialdehyde; Maze Learning; Mice; Neuroprotective Agents; Superoxide Dismutase; Time Factors; Vinca Alkaloids

Topics: Animals; Calbindin 2; Calcium Channel Blockers; Disease Models, Animal; Ependymoglial Cells; Immunohistochemistry; Ischemia; Microscopy, Confocal; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases; Retinal Neurons; Vinca Alkaloids

Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphodiesterase 5 Inhibitors; Renal Artery; Renal Circulation; Sildenafil Citrate; Vasodilation; Vasodilator Agents; Vinca Alkaloids

Topics: 4-Aminopyridine; Acoustic Stimulation; Animals; Anticonvulsants; Auditory Threshold; Carbamazepine; Disease Models, Animal; Drug Interactions; Evoked Potentials, Auditory; Guinea Pigs; Hearing Loss; Male; Psychoacoustics; Seizures; Time Factors; Vinca Alkaloids

Topics: Animals; Disease Models, Animal; Entorhinal Cortex; Male; Maze Learning; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Vinca Alkaloids

Topics: Animals; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Female; Ferrets; Fetal Alcohol Spectrum Disorders; Phosphodiesterase Inhibitors; Phosphorylation; Pregnancy; Vinca Alkaloids

Topics: Alcohol Drinking; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Depressants; Cyclic AMP; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Male; Mice; Motor Activity; Phosphodiesterase Inhibitors; Pregnancy; Pregnancy Complications; Single-Blind Method; Survival Rate; Vinca Alkaloids; Weight Gain

Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Colon; Disease Models, Animal; Female; Ischemia; Male; Pentoxifylline; Rats; Rats, Wistar; Vasodilator Agents; Vinca Alkaloids; Wound Healing

Topics: Animals; Brain Ischemia; Disease Models, Animal; Humans; Ischemic Attack, Transient; Neuroprotective Agents; Rats; Stroke; Structure-Activity Relationship; Vinca Alkaloids

Topics: Animals; Disease Models, Animal; Ethanol; Female; Ferrets; Fetal Alcohol Spectrum Disorders; Neuronal Plasticity; Phosphodiesterase I; Phosphodiesterase Inhibitors; Pregnancy; Vinca Alkaloids

Topics: Analgesics; Animals; Axonal Transport; Disease Models, Animal; Male; Nerve Degeneration; Pain; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord; Vinca Alkaloids

Topics: Animals; Brain; Cerebrovascular Disorders; Disease Models, Animal; Humans; Injections, Intravenous; Macaca fascicularis; Platelet Aggregation Inhibitors; Radioligand Assay; Tomography, Emission-Computed; Vinca Alkaloids

Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Guinea Pigs; Hearing Loss, Sensorineural; Male; Organ of Corti; Sisomicin; Vinca Alkaloids

Topics: Animals; Cerebrovascular Circulation; Disease Models, Animal; Hippocampus; Ischemic Attack, Transient; Male; Organ Specificity; Rats; Rats, Inbred Strains; Reference Values; Vasodilator Agents; Vinca Alkaloids

Topics: Acid-Base Equilibrium; Animals; Blood Pressure; Cats; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Epoprostenol; Fibrinolytic Agents; Intracranial Embolism and Thrombosis; Methods; Papaverine; Platelet Aggregation; Vasodilator Agents; Verapamil; Vinca Alkaloids