viloxazine and Aura
viloxazine has been researched along with Aura in 8 studies
Viloxazine: A morpholine derivative used as an antidepressant. It is similar in action to IMIPRAMINE.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " for 10 days) on the steady-state plasma concentrations of Oxcarbazepine (OXC), its active metabolite 10, 11-dihydro-10-hydroxy-carbazepine (MHD) and the corresponding diol (DHD) were studied in a randomized, double-blind cross-over placebo-controlled trial in 6 epileptic patients stabilized on a fixed dosage of OXC." | 6.67 | Effects of the antidepressant drug viloxazine on oxcarbazepine and its hydroxylated metabolites in patients with epilepsy. ( Artesi, C; Di Perri, R; Fazio, A; Oteri, G; Perucca, E; Pisani, F; Xiao, B, 1994) |
| " for 10 days) on the steady-state plasma concentrations of Oxcarbazepine (OXC), its active metabolite 10, 11-dihydro-10-hydroxy-carbazepine (MHD) and the corresponding diol (DHD) were studied in a randomized, double-blind cross-over placebo-controlled trial in 6 epileptic patients stabilized on a fixed dosage of OXC." | 2.67 | Effects of the antidepressant drug viloxazine on oxcarbazepine and its hydroxylated metabolites in patients with epilepsy. ( Artesi, C; Di Perri, R; Fazio, A; Oteri, G; Perucca, E; Pisani, F; Xiao, B, 1994) |
| "On the average, seizures were observed at 40 mg/kg and were seen after desmethylimipramine (50 mg/kg), mianserin (30 mg/kg), amitriptyline (20 mg/kg), imipramine (40 mg/kg), maprotiline (40 mg/kg), and zimelidine (50 mg/kg)." | 1.27 | Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model. ( Bradford, D; Krijzer, F; Snelder, M, 1984) |
| " Clearance and volume of distribution calculated after IV dosing in the patients were 124 +/- 11 ml h-1 kg-1 and 0." | 1.27 | Pharmacokinetics of the antidepressant drug viloxazine in normal subjects and in epileptic patients receiving chronic anticonvulsant treatment. ( Artesi, C; Fazio, A; Perucca, E; Pisani, B; Pisani, F; Russo, M; Spina, E; Trio, R, 1986) |
| " Pharmacokinetic studies in the mouse showed peak plasma levels to occur 30 min following oral doses, with a mean half-life of 58 min." | 1.26 | Anticonvulsant and proconvulsant properties of viloxazine hydrochloride: pharmacological and pharmacokinetic studies in rodents and the epileptic baboon. ( Adam, HK; Anlezark, GM; Greenwood, DT; Meldrum, BS, 1982) |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Krijzer, F | 1 |
| Snelder, M | 1 |
| Bradford, D | 1 |
| Pisani, F | 5 |
| Narbone, MC | 1 |
| Fazio, A | 5 |
| Crisafulli, P | 1 |
| Primerano, G | 1 |
| D'Agostino, AA | 1 |
| Oteri, G | 4 |
| Di Perri, R | 4 |
| Meldrum, BS | 1 |
| Anlezark, GM | 1 |
| Adam, HK | 1 |
| Greenwood, DT | 1 |
| Artesi, C | 3 |
| Xiao, B | 1 |
| Perucca, E | 4 |
| Trimble, M | 1 |
| Russo, M | 3 |
| Trio, R | 3 |
| Spina, E | 1 |
| Pisani, B | 2 |
Reviews
1 review available for viloxazine and Aura
| Article | Year |
|---|---|
Non-monoamine oxidase inhibitor antidepressants and epilepsy: a review.
Topics: Adult; Aged; Amines; Animals; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricycl | 1978 |
Trials
1 trial available for viloxazine and Aura
| Article | Year |
|---|---|
Effects of the antidepressant drug viloxazine on oxcarbazepine and its hydroxylated metabolites in patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Cross-Over Studies; Depressive Disorder; Double-Blind Method; | 1994 |
Other Studies
6 other studies available for viloxazine and Aura
| Article | Year |
|---|---|
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Re | 1984 |
Effect of viloxazine on serum carbamazepine levels in epileptic patients.
Topics: Adult; Carbamazepine; Depression; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Mo | 1984 |
Anticonvulsant and proconvulsant properties of viloxazine hydrochloride: pharmacological and pharmacokinetic studies in rodents and the epileptic baboon.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Convulsants; Electroshock; Epilepsy; Female; Kinetic | 1982 |
Elevation of plasma phenytoin by viloxazine in epileptic patients: a clinically significant drug interaction.
Topics: Adult; Aged; Depressive Disorder; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Ph | 1992 |
Pharmacokinetics of the antidepressant drug viloxazine in normal subjects and in epileptic patients receiving chronic anticonvulsant treatment.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Drug Interactions; Epilepsy; Female; Humans; Injectio | 1986 |
Carbamazepine-viloxazine interaction in patients with epilepsy.
Topics: Adult; Carbamazepine; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Epilepsy; F | 1986 |